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Biodiversity as an insurAnce against environmental CHange – BACH
In a world increasingly perturbed by human activities it is now urgent to evaluate the potential role of biodiversity on shaping ecosystems properties and services. To this end it is necessary to both understand the mechanisms that drive species richness dynamics and their relationships with ecosyst
From cable robot to active structure: application to additive manufacturing – CABTIVE
The development potential of Additive Manufacturing (AM) in the coming years is very significant, particularly in the aerospace and medical sectors. This process, the mastery and development of which are at the heart of the challenges of the Industry of the Future, is set to boost productivity and t
Real Monge-Ampère and Kähler geometry of homogeneous spaces – MARGE
The project MARGE is a project in fundamental Mathematics on the existence of canonical metrics, a central problem in complex geometry. The quest for canonical metrics on complex manifolds is a natural generalization of the metric aspects of Riemann's uniformization theorem. Major breakthroughs in t
Le documentaire [Sargasses : enquête sur une algue à la dérive] est en ligne
Ce 24 octobre, dans l’amphithéâtre de l’Institut de physique du globe de Paris (IPGP), Sargasses : enquête sur une algue à la dérive a fait salle comble. Présenté en avant-première dans le cadre de Pariscience, le festival international de films scientifiques, le public s’est pressé pour découvr
Structural geometric approximation for algorithms – SAGA
Combinatorial optimization arises naturally in a variety of resource management problems in public transportation companies, industrial manufacturing, financial and health-care institutions. Standing out are two categories of optimization problems, packing and covering, with applications in material
Synthesis of pyrazoline derivatives via [3+2] cyclization. Towards an asymmetric and catalytic version of the reaction. – HUISPHOS
Instead of using a large quantity of phosphine, we suggest to regenerate in situ the catalyst, and so to aim towards a more environmentally friendly chemistry. We developed the first examples of catalytic cyclization reactions between the Huisgen zwitterion and alpha-ketoester derivatives. We verifi
Role of glomerular inhibition in olfactory processing – Glom Inhib
The olfactory bulb is the first relay station for odor processing in the brain. It receives olfactory sensory information from olfactory sensory neurons that detect odorants in the nasal epithelium. The vast majority of olfactory bulb neurons are inhibitory interneurons that modulate the activity of
Early determinants of adult lung diseases: a role for perinatal exposure to nanoparticles? – EarlyNanoPathoLung
Les données expérimentales s'accumulent pour témoigner qu'il peut exister des effets adverses après exposition respiratoire aux nanoparticules chez l'adulte. Bien qu'il soit largement accepté qu'une exposition pendant la grossesse peut influencer de façon significative le développement fœtal et la m
Toxicity of dolutegravir and evaluation of doravirine for alternative 1st line antiretroviral treatment in people living with HIV – ELDORADO
Depuis 2018, l'Organisation Mondiale de la Santé recommande le dolutégravir (DTG), un inhibiteur de l'intégrase, comme traitement antirétroviral de première intention chez les adultes vivant avec le VIH-1. De plus en plus de preuves montrent que le traitement antirétroviral à base de DTG est associé
Epigenome dysregulation in link with substance use and mental health in young people – EPI_young
Epigenetic regulation is crucial for neuronal functioning and synaptic plasticity and epigenetic mechanisms were consistently reported as highly involved in pathophysiology of psychiatric disorders. Epigenetic dysregulation could account for the high heterogeneity of these disorders, their phenotypi
