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A new generation of light sheet microscope: mesofluidics and artificial assistant – Phy-ASA2018
The program of BioEmergences-PhaseView Joint Laboratory (LabCom) is the development of an innovative range of microscopes based on the light sheet technologty (SPIM) that meets the specifications of a new integrative biology. The challenge of the field is to found a reconstruction of multi-level dyn
A new humanitarian Agenda for UNESCO: protecting cultural heritage through local communities – HUMANITIES
Between 2012 and 2015, a slew of historical sites registered on the World Heritage List were systematically targeted by terrorist groups in Mali, Iraq, and Syria. In response to this crisis, UNESCO adopted a strategy aiming at ‘incorporat[ing] the protection of culture into humanitarian action, secu
A new layer in CoA/Ac-CoA metabolism by NME proteins – NME_CoA
The regulated management of the cellular pool of Actyl-Coenzyme A (Ac-CoA) is of critical importance for the life of all organisms. Depending on the energy status of cells, Ac-CoA can be used either in lipid synthesis and storage or in a complex signalling process leading to histone acetylation and
A new non-human primate model for translational brain research – Marmobrain
Thanks to their homology with humans at multiple levels, non-human primates are key animal models for investigating the neural underpinnings of brain functions in normal or pathological conditions. Over the last 5 years, the marmoset monkey model has quickly established itself as a worldwide new st
A novel integrated and sustainable approach to monitor and control Bluetongue in the Mediterranean region – Blue-Med
It is well established that world’s climate change influences the emergence of diseases particularly vector-borne diseases (VBDs). This project deals with Bluetongue (BT) which has been one of the most feared VBDs affecting the Mediterranean region. BT virus (BTV) is characterized by having multiple
A novel molecular tracing system for rice and citrus pathogenic Xanthomonas – XANTHracing
The originality and novelty of this project reside on the identification, characterization, sequencing of CRISPR loci (Clustered Regularly Interspaced Short Palindromic Repeats) and VNTR (variable number of tandem repeats) in a large collection of strains of Xanthomonas oryzae and Xanthomonas citri.
A novel multi-stage acting antimalarial drug-candidate – plasmodrug
Malaria is still a major public health problem in 2018, since this infection due to the Plasmodium parasite, present in 91 countries, kills more than 440,000 people every year, with a majority of African children. As observed in most of infectious diseases, the emergence of resistant strains of P. f
A novel sensing method for the detection of pharmaceuticals in water – DETECMED
Micropollutants, among them pharmaceuticals, represent an alarming concern for water quality due to their toxicity, persistence, and low removal rate by conventional water treatments. The EU parliament pointed to the need for innovative solutions for treatment but also control of those emerging poll
A novel strategy to maximize survival of primary and iPS-derived pancreatic islets after transplantation – MAXI-ISLETS
Pancreatic islet transplantation, which entails the intraportal injection of islets sourced from either deceased donors or induced pluripotent stem cells (iPS), provides substantial benefits for individuals with Type 1 Diabetes. However, the low yield of the procedure due to ischemia-reperfusion inj
A novel ultrasound 2-phase flow instrumentation for SEDiment transport EXPeriments & modelling – 2-phaseSEDEXP
The rate of natural sediments transported by fluvial, estuarine or coastal flows, commonly named the solid transport flow rate, represents the physical quantity to be expressed mathematically as a function of the hydrosedimentary quantities of the flow in order to predict its morphological evolution
