Preannouncement: The transnational call for proposals on cardiovascular diseases (ERA-CVD Joint Transnational Call 2016)
Cardiovascular diseases are the largest cause of death in the European Union, as they account for around 2 million deaths per year. Overall, cardiovascular diseases are estimated to cause the economy of the European Union costs of almost 196 billion Euros a year. Furthermore, they are one of the leading causes of long-term sickness, chronic diseases and loss to the labour market. Therefore, cardiovascular diseases are a major health and socioeconomic problem in Europe.
The present and future challenges in cardiovascular research can only be met by an effective cooperation at transnational level. To achieve this goal, an effective coordination of research at national and European Union level, increased cross-disciplinary interaction and research advancements are needed. In this context, the newly established ERA-NET on cardiovascular diseases (ERA-CVD) will foster new but also extend existing transnational cooperation of European countries on cardiovascular diseases research.
Promoting European and international research on Heart Failure
The aim of the call is to enable scientists in different countries to build an effective collaboration on common interdisciplinary research projects based on complementarities and sharing of expertise in the field of Heart Failure, with a clear translational research approach. Research should focus on the association between precipitating or causative factors (e.g. metabolic factors), and the molecular effectors and organ dysfunction in the development and progression of Heart Failure with reduced ejection fraction and Heart Failure with preserved ejection fraction. Research proposals should have a translational perspective, with potential impact on disease severity and outcome.
Transnational research proposals must cover at least one of the sub-topics proposed below, which are equal in relevance for this call:
- Earlier recognition and prognosis of Heart Failure;
- Innovative approaches to prevent and treat Heart Failure or to reverse the remodelling process;
- Role of the interface between myocardium and non-myocyte cells in pathophysiology of heart failure.
Additionally, each proposal should consider, where appropriate, the following cross-sectional aspects:
- Interdisciplinary approach for Heart Failure research.
- Research on gender differences in Heart Failure.
Promoting multi-disciplinary work and translational research
Multi-disciplinary work and translational research proposals that combine basic and clinical approaches are encouraged. Consortia are also encouraged to demonstrate engagement with industry. Likewise, the participation of patient organizations will be considered as added value, where appropriate.
The following approaches are excluded from the scope of the call:
- Interventional clinical trials
- Building up of new cohorts, registries and/or biomaterial banks
- Biomarker fishing experiments
The deadline for proposal pre-registration is March 8, 2016.
The deadline for proposal submission is June 17, 2016.
For more information, visit our website www.ERA-CVD.eu
