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Increasing Sustainability through Tolerance Allocation and Quality Control Strategies in high Precision Manufacturing - Application on Hydrogen Valves – H2-TACTICS
EU-Sustainable Products Regulation based on new Eco-design Directive aims to substantially enhance circularity, energy efficiency, and overall environmental sustainability of products sold within the EU. Integrating environmental considerations into every phase of the product lifecycle plays a cruci
Individual muscle Coordination strategies and their role in the development of musculoskeletal disorders – COMMODE
Our primary testable hypothesis is that each individual has unique muscle coordination strategies that will have specific mechanical effects on his/her MSK system. As such, some strategies would make people more at risk of developing MSK disorders than others. This hypothesis was presented in an inv
Inductive Biases for Compositionality-capable Deep Learning Models of Natural Language – COMPO
In Natural language processing, large deep learning-based language models have substantially changed the field in the last few years. However, we observe that these models sometimes fail in cases where humans do not have particular problems. The COMPO project proposes to design new models with b
Influence of m6A methylation of influenza A virus RNA on the host innate immune response – METHAFLU
Today, there is a real revolution in therapeutic applications using or targeting nucleic acids (mRNA vaccines, antisense oligonucleotides (ASO) or siRNA). In addition, the role of RNA methylation and its diversity in human disease is emerging alongside that of DNA. The impact of DNA hypermethylat
Infrared multispectral tissue imaging to improve stratification for patients with head and neck cancer – TUMADMIR
Head and neck tumors are clinically and pathologically heterogeneous. While the vast majority of them arise from the malignant transformation of the squamous epithelium covering the upper aerodigestive tract, and are therefore squamous cell carcinomas, several histological subtypes have been descri
Infrastructure technologique pour la recherche d’excellence en robotique
TIRREX va coordonner au niveau national le développement et l’accès à de nouvelles plateformes de robotique. Les grands acteurs de la recherche en robotique (CNRS, INRIA, CEA et INRAE) sont rassemblés dans ce projet, qui s’articule autour de six axes thématiques et de trois axes transver
Ingénierie à façon de glycoenzymes par des outils de criblage virtuel innovants pour le design de vaccins entériques – GLUCODESIGN
Scientific context: Shigella flexneri are enteroinvasive Gram negative bacteria responsible for endemic shigellosis, or bacillary dysentery. To fight this major burden, especially in children under 5 years of age, vaccines ensuring multi-serotype coverage are in demand. New glycovaccines based on sy
InnovAI: Co-Creating with Artificial Intelligence – InnovAI
This project examines the transformative potential of generative AI technologies in the creativity processes. While research has discussed the potential uses of AI in creative processes, empirical studies are scarce. Our research addresses three questions: (1) How can we work with AI to foster crea
Innovative Air Monitoring Laboratory – IAM-Lab
In 2014, an INSEE survey showed that air quality was the main concern of the French, ahead of climate change, yet the monitoring of regulated pollutants shows that the limit values are not always respected for several regulated outdoor air pollutants. However, air quality is not limited to atmospher
Innovative Aquifers Governance for Resilient Water Management and Sustainable Ecosystems in Stressed Mediterranean Agricultural Areas – AGREEMed
Aquifers are a critical component of the water cycle, the ecosystems, and the socio-economic systems; especially in the southern shore of the Mediterranean, where water resources are limited and unevenly distributed in space and time. Some countries receive a mere 10% of the local total annual avera
