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Neurotensin-polyplex: Tool for a novel gene therapy of Non Small Cell Lung Cancer – NTS-polyplex
Lung cancer is the main cause of death from cancer with 5-year survival across all stages at 15-20%. About 80% of these tumors are from non–small-cell histological type (NSCLC), including adenocarcinomas, squamous cell, and large cell carcinomas. Surgery is generally accepted as the best treatment o
New technologies for a fast and personalized treatment of aortic lesions
Cette première année a permis aux différentes équipes de s’organiser et de se coordonner pour lancer le projet EndoVx. Le développement d’une plateforme digitale et d’outils digitaux innovants a débuté par le déploiement du logiciel ARVA qui calcule automatiquement les dia
Next generation medicine for renal ciliopathies
Les ciliopathies sont un groupe important de maladies génétiques rares et graves causées par un dysfonctionnement du cil primaire. Dû à la variabilité phénotypique considérable associée aux mutations d'un gène de ciliopathie donné, il est difficile de prédire la gravité de la maladie ainsi que le ri
Observation of the territory for the understanding of the evolution of administrative boundaries and settlements. Building Geo-Historical data bases and Ontological approach. – GéoPeuple
/ / / / History of the French population and territory since the 18th century until now is quite well known at the department's and province's level. However, it is far less explored at the scale of the smallest administrative units, the communes, where the people have their everyday life. The reaso
Original Measurement of Energy using a Geometrical Approach – OMEGA
Since the discovery of the accelerating expansion of the Universe in 1998, understanding the nature of dark energy, or highlighting a change in the laws of general relativity scale, has become one of the major challenges of modern cosmology. From the observational point of view, it is necessary to h
PaRis Artificial Intelligence Research InstitutE
Créé en 2019 par le CNRS, Inria, l'Institut Pasteur, l'Université PSL, l'Université Paris Cité, et un club de partenaires industriels, PRAIRIE (PaRis Artificial Intelligence Research InstitutE) est l'un des 4 Instituts interdisciplinaires de recherche en intelligence artificielle (« 3IA ») mis en pl
Phosphoinositides, cytoskeleton and platelet activation – PHOSPHOINOPLAT
Platelets are critical for normal haemostasis but are also centrally involved in pathological processes like thrombosis and atherosclerosis. Their deregulation can lead to bleeding or to arterial thrombosis, a primary cause of heart attack and ischemic stroke. Recently, they have also been implicate
Physical and Intrinsic Security of Embedded Neural Networks – PICTURE
Today, a major challenge in Machine Learning (ML) is edge-deployed models and more particularly neural networks in a large variety of embedded platforms with high interests shown on porting deep neural networks (DNN) for inference purpose. Many reasons explain the direct use of neural networks on ed
Physiologic and molecular determinant of brain susceptibility to reward- and metabolic-based diseases – BrainHealth
Obesity has reached a pandemic level and there is an urge to identify vulnerability/protective factors. Evidence support that obesity results from an interaction between genes and food environment. the TaqI A1 single nucleotide polymorphism is widely present in the population and has been identified
