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Reconstructing regional BuRnt Areas from microcharcoal preserved In marine SEdiments – BRAISE
BRAISE has four objectives: (a) create the first dataset of charcoal accumulation in marine sediments of modern ages; (b) identify spatial patterns in the distribution of charcoal accumulation in a given area, construct hypotheses about its processes and determine local and/or regional scale correct
Optimizing Paralympic performance: from detection to medal-winning
L’objectif est de comprendre les enjeux de la très haute performance paralympique et de proposer des outils au service des athlètes afin d’optimiser leur performance jusqu’aux Jeux de Paris 2024. La Fondation EDF participe au projet grâce à un mécénat de compétence. Trois axes composent le projet :
The Toulouse-Perpignan
Le projet TULIP-GS vise à dynamiser la recherche et la formation à l'interface entre la biologie fonctionnelle, l'écologie et l'évolution. Il vise aussi à développer l'autonomie des jeunes scientifiques, à promouvoir l'apprentissage par la pratique et les liens avec le monde socio-économique. Pour r
Tribological reliability of amorphous metallic alloys – TriboRAMA
Due to their exceptional mechanical properties coupled with very tight tolerances during casting, the involvement of bulk metallic glasses in micromechanics remains unexploited due to their unpredictable tribological behaviour. The objective of the project is to improve the understanding of the phen
Access to perceptual ambiguity: Behavioral, metacognitive, and physiological measures of perception under conditions of uncertainty – AMBISENSE
In the current project, we propose to investigate the nature and conditions of access to stimulus ambiguity. We will examine three main factors: the characteristics of the stimulus; its context; the expertise of observers. We will also collect different measures of access to ambiguity: behavioral pe
Genomic factors underlying the effect of Respiratory Viruses and Allergens in Asthma – NIRVANA
The central hypothesis that the host genotype plays an important role in the effects of respiratory allergens and viruses in asthma is supported by several observations, but has still never been deeply addressed. New technologies based on microarrays allow accurate and comprehensive characterization
DEVELOPMENT OF CARBON MONOXIDE-RELEASING MOLECULES CONJUGATED TO POLYSACCHARIDE CARRIERS TARGETING ADIPOSE TISSUE FOR THE TREATMENT OF OBESITY – SWEET-CO
We work with chemists to produce analogs of CORM-401 conjugated with another molecule that may target CO to the adipose tissue. This idea was inspired by a publication that used a similar strategy to enhance the accumulation of anti-inflammatory drugs in this tissue. CO released by CORM-401 is known
Correlative Scanning Precession Electron Diffraction and Atom Probe Tomography to access the 3D polycrystalline grain microstructure of nanomaterials – 3D_SPED_APT
Coupling the Scanning Precession Electron Diffraction (SPED) technique with sample tilts and tomographic post-processing routines is expected to enable the reconstruction of 3D phase and orientation maps and consequently to provide access to the interfaces or interphases geometric and crystallograph
3D Bragg ptychography: Developments for metallic nano-twinned thin films – PtyMet
The project is built on two objectives: the first concerns materials, the second is more methodological. Indeed, we want to develop nano-twinned gold thin films. We believe that these films will combine ductility (because gold is initially ductile and that the twins can migrate or enlarge), mechanic
The LINE-1 regulatory network: genome-wide impact of recent transposable elements on mammalian genic activity – ImpacTE
Repetitive DNA sequences account for almost half of the human and mouse genomes. Most of them are degenerated remnants of ancient mobile genetic elements. However, a subset of evolutionary recent transposable elements, particularly those belonging to the LINE-1 (L1) retrotransposon family, actively