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Structural dynamics of a dimeric GPCR at the single molecule level – DynaMuR2
The objectives of this program are to be able to record the different conformational changes of the mGlu2 receptor. This receptor consists of two subunits, and each of them is made of «main structured domains: the binding domain, the cysteine-rich linker, and the membrane domain. We want to record t
Robot collaboratif – CoBot
To date, the necessary safety conditions for collaboration between machine and man have not been met. Humans have a flexible architecture and their behaviour has been largely optimised in the course of evolution. Despite the technological progress of recent years, no robot can yet collaborate with h
Designing n-type Zintl phases for thermoelectric power generation applications – DENZIP
The thermoelectric properties of a material are characterized by the dimensionless thermoelectric figure of merit ZT defined as the ratio of the thermopower (also known as the Seebeck coefficient) squared times the absolute temperature divided by the product of the electrical resistivity by the tota
World Wide Web of Plankton Image Curation – WWW.PIC
In environmental sciences, common questions are: how many organisms are present in a given environment? How diverse are they? Does that change in time? Digital imaging can help answer these questions, particularly underwater, where direct observation by humans is difficult. For example, images of bi
Cellular repair and toxicity determinants of the major oxidative DNA lesion thymine glycol – TG-TOX
The main objectives of the project are: 1/ to investigate the contributions of individual DNA glycosylases, NTH1 and NEIL1, initiating the Base Excision Repair pathway (BER) to repair of TG; 2/ to elucidate the molecular mechanisms regulating the recruitment of DNA glycosylases to damage sites in th
Dissecting the molecular interactions of mitochondrial glutaredoxin S15 in plants – mitoglu
The recent demonstration that GRXS15 coordinates an [2Fe-2S] cluster using glutathione molecules which can be transferred to an acceptor protein and that null mutants for the mitochondrial GRXS15 in Arabidopsis are embryo-lethal provided clear evidence that GRXS15 is an essential component of the IS
PARAMOUNT: Production of Aerosol paRticle orgAnic Matter in ClOUds: chamber and laboratory studies, mechanisms, modelling and iNTegration – PARAMOUNT
Chemical processes in clouds have been suggested to contribute substantially to organic aerosol particle mass since a long time. Recent evidence from the HCCT-2010 field study and the CUMULUS chamber study suggest that this organic mass production can be substantial and depends on the concentration
Impact du changement climatique à l'échelle du kilomètre en Europe
L’objectif principal du projet km-impacts consiste à quantifier les impacts du changement climatique sur les crues éclairs, le climat urbain et les processus météorologiques propres aux îles Méditerranéennes en tirant profit d’une nouvelle génération de modèles régionaux de climat (MRC) qui utilise
Impact of a school-based autism anti-stigma intervention: the IDEAL program – IDEAL
In particular, several recent studies highlight the existence of negative attitudes from other children towards children with ASD within the school (e.g. Humphrey & Hebron, 2015). Teachers and parents of pupils may also have many reservations about the inclusion of these children in school, sometim
PIGIMMUNITY: a systems biology approach to boost innate immunity in the pig – PIGIMMUNITY
Great efforts are being directed into the search of new alternative methods to antibiotics. Among those, stimulation of innate immunity has been identified as a promising prophylactic and/or therapeutic strategy to combat infectious diseases due to their ability to activate host immune mechanisms wi
