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Role of the SAGA co-activator complex in transcription during cell differentiation in mammals – SAGA-Retina
To regulate gene expression, activators bind specific DNA sequences at gene regulatory elements where they recruit coactivator complexes which open the chromatin structure at promoters to facilitate the assembly of the preinitiation complex, composed of general transcription factors and RNAPII. SAGA
Projet IngéPLUS d'ouverture sociale des écoles d'ingénieurs par la diversification des cursus
4éme année du projet IngéPLUS, l’année universitaire 2022-2023 a été marquée par : L’intégration des étudiants IngéPLUS en école d’ingénieur à la rentrée 2022 Le taux de réussite en licence et Bachelor à 97% pour la 1ere promotion IngéPLUS
Multi-Modal Multi-person Low-Level Learning for Robot Interaction – ML3RI
Besides the common struggle due to the health crisis, and the fact that all our meetings were held through a screen, thus limiting the interaction and making the understanding more difficult, we were severely constrained by the fact that we could not record data in our laboratory. This made impossib
Nanoscale thermal sensing using hybrid diamond sensors – THESEUS
The sensor will be based on a novel design of hybrid architecture, building on a transduction of temperature changes on magnetic changes probed by single electronic spins in a diamond. Ultimate performances will be achieved by capitalizing in an innovative manner on (i) the unique sensitivity of dia
Odorant Binding Proteins-based biomimetic optical nose – OBP-optinose
Today, there is a growing demand for sensitive and selective detection of volatile organic compounds (VOCs) in various domains such as environment monitoring, public safety, quality control, non-invasive medical diagnostics. Traditional methods, though accurate and reliable, require expensive equipm
Modulating gene expression by nucleus positioning in mouse oocytes – NuPos
In this interdisciplinary project we wanted to explore the mechanisms and biological significance of nuclear centering in the mouse oocyte. The position of the nucleus within cells often plays the role of a morphogen and an abnormal position can cause disease. In murine or human oocytes, the central
Food policies in France: innovation and reconfigurations of public action – POLAL
The POLAL project questions the evolutions of contemporary public policies. It associates five research units: CSO, IRISSO, CMH, CERPAS and IDEES. The project explores two sets of questions, drawing upon the results established by the literature on recent changes in public intervention, regarding ho
Raw earth construction vulnerability regarding hydric conditions – VBATCH
There are 3 objectives : - The analysis of the liquid water content on the mechanical behavour in rammed earth. We aim to characterize : compressive strength, Young modulous, cohesion and friction angles. - The modelling of the hydromechanical behaviour, using the concept of effective stress, us
A novel mechanically enhanced bioleaching process – BIOMECALIX
The BIOMECALIX project is positioned in the general context of extractive metallurgy in support of the energy and digital transition, and aims to improve existing technologies enabling the primary (from ores) or secondary (waste to be recycled) production of metals. In particular, the leaching stage
Oral exposure and gut-targeted toxicity of PFOA and its precursor 8:2 FTOH under chronic stress: when high-resolution chemical imaging bridges food toxicology – FLUO-GUT
Le tractus digestif est la première barrière physique et biologique contre le PFOA après exposition orale, et en même temps sa première cible. Toutefois, ses effets sur la paroi intestinale restent, à ce jour, largement méconnus. Par ailleurs, dans nos sociétés occidentales, l’Homme contemporain est