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Identification of SARS-Cov-2 neutralizing Affitins – COVAFFIT
The emergence in 2019 of a new severe acute respiratory syndrome coronavirus (SARS-CoV-2) has led to a global pandemic with nearly 31 million infected people of whom nearly 1 million have died. This virus is particularly contagious and uses the S protein (or spike protein) through its RBD domain to
Serological survey of SARS-CoV-2 in blood donors in sub-Saharan African: evaluation of viral dissemination via the Francophone Africa Blood Transfusion Research Network – AFRACOV2
Since December 2019, a novel human coronavirus, SARS-CoV-2, has emerged from China where the first cases of the COVID-19 were described. By October 2020, more than 38 million cases have been reported worldwide, including more than 1.1 million deaths. In Africa, 1.6 million individual would have been
Development and characterization of electronic noses for the rapid detection of COVID-19 in exhaled breath – COVINose
Early, easy and rapid diagnosis of coronavirus disease 2019 (COVID-19) is of the utmost importance but remains challenging. Breath analysis is an innovative, non-invasive, real-time, point-of-care technique for detecting volatile organic compounds (VOCs) in expired breath with potential for use in d
Natural History of SARS-CoV2 : Emergence and Reservoir – DisCoVer
In late December 2019, a new disease named COVID-19 (COronaVirus Infectious Disease 2019), due to a new Betacoronavirus, the SARS-CoV-2, was notified in Wuhan, China. WHO declares “A public health emergency of international concern” on January 30th, 2020. A few weeks later, the virus has spread in m
COVID 19 Rapid diagnosis test (development and clinical validation in 7 weeks) – CORaDiag
COVID-19 is an acute respiratory disease caused by novel coronavirus SARS-CoV-2 also known as 2019-nCoV. On March 11, 2020, the World Health Organization (WHO) characterized COVID-19 as a pandemic. The disease is spreading worldwide. The World Health Organization has declared a global health emergen
Acoustic and Optic bioSensors for label-free CoVId-19 fast diagnosis – AcOstoVie
The world is currently facing a pandemic of a new emerging virus from the coronavirus family named COVID-19. Detection of infected patients is crucial to break the epidemic situation. As a consequence it is essential to diagnose fast and in large number populations to sort rapidly those who are infe
Clinical proteomic characterization of the SARS-CoV-2 Spike protein to optimize its detection and the development of serological assays – proteoCOVID
Following the emergence and global spread of a new coronavirus called SARS-CoV-2, there is an urgent need to explore various aspects of this new disease, including its mode of transmission, virus-host interactions and immune response, diagnosis and therapy. This collaborative project leverages the c
Toward an integrated surveillance of potential zoonotic Betacoronaviruses in the wild animal value chain of Cambodia – ZooCov
Naturally hosted in wild animals such as bats, betacoronaviruses (beta-CoVs) are responsible for severe and fatal human respiratory infections. Data and knowledge on animal reservoir, but also knowledge on cultural, sociological and ecological factors driving beta-CoVs spread to humans and emergence
Human colonic organoids as a model to study SARS-CoV-2 variants infection – Organovir
Our proposal aims to monitor the ability of SARS-CoV-2 variants of concern, including South Africa, United Kingdom and Brazil ones, to infect human colonic organoid-derived cell monolayers, a model of choice to study host pathogen interaction in a standardized and reproducible way closely mimicking
Pre-pandemic SARS-CoV-2 natural immunity in Africa and South-East Asia – PRECOV_
Almost two years after the emergence of COVID-19, significant regional differences persist, showing the lowest incidence rates in sub-Saharan Africa, Southeast Asia, and Oceania. This trend was observed at the onset of the epidemic and has been confirmed during subsequent epidemic waves. Several