Search for a funded project
Explorez notre base de projets financés
Restriction policies and conflict worldwide during the Covid-19 pandemic – covidco
The first aim of the project is to provide real-time evidence of the effect of restriction policies to flatten the epidemic curve (i.e., restrictions to economic activity and mobility) on the intensity of conflict worldwide. Thanks to daily information on conflict events with specific details on the
Structural and functional outcomes of epitranscriptomic methylation of (+)RNA virus genomes – VIRAGE
The emergence of important viral human pathogens (eg., Dengue, Zika, SARS, MERS, Ebola viruses) cause substantial health and economic burden. These RNA viruses can rapidly evolve and escape antiviral responses by hiding their RNAs from detection by antiviral sensors. Their viral replication/transcri
Characterization of the microVAScular dysfunction in COvid-19 ARDS. – VASCO
To establish the prognostic value of the alveolar-dead space (measured iteratively) in patients with COVID-19 and non-COVID-19 ARDS. Establish the respective influences of the biological parameters of endothelial damage, of the biological parameters of coagulopathy, of the parameters set on the art
Involvement of circulating fibrocytes in pathophysiology and prognosis of COVID-19 pneumonia – FIBROCO
We hypothesized that circulating fibrocytes could be a valuable biomarker during COVID-19 pneumonia. We aimed to determine the involvement of fibrocytes during COVID-19 pneumonia, and to determine if fibrocytes could be associated with prognosis. We included 57 patients in the Hospitalized group (me
Early identification of risk associated with drugs used in COVID-19: analysis of global pharmacovigilance data – Vigi-Drugs COVID-19
This project aims to investigate and characterise early the major adverse drug reactions of drugs used and/or approved for the treatment of patients with Covid19. The analyses are based on the WHO global pharmacovigilance database: VigiBase® containing more than 27 million adverse drug reactions,
Molecular role of the viral nucleoprotein in the SARS-Cov-2 replication cycle – SARS2NUCLEOPROTEIN
In order to develop rational strategies for the development of inhibitors of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) it is essential to understand the molecular basis of different aspects of the viral cycle. Coronaviruses are enveloped positive-sense single strand RNA viruses th
Endothelial damage and repair in SARS-CoV-2 related vascular injury – ENDOCOV-19
Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and can present with a range of manifestations. SARS-CoV-2 infects type II pneumocytes by binding to membrane-bound angiotensin-converting enzyme 2 (ACE2). Rapidly after the outbreak, re
Interventions for Covid-19 infection: a living mapping of research and a series of living network meta-analyses – living-NMA-covid
Context: In December 2019, a novel coronavirus outbreak was documented in Wuhan, Hubei Province, China. Over the first 6 weeks of the new decade, this novel coronavirus, known as SARS-CoV-2, has spread from China to 20 other countries and WHO recently characterized Covid-19 as a pandemic. To overcom
Prospective analysis of morbi-mortality of patients with cancers in active phase of medical treatment suspected or diagnosed of a SARS-COV2 infection. – ONCOVID-19
Since December 2019, the novel coronavirus (SRAS-COV2, causing an emerging infectious disease called COVID-19) has spread quickly worldwide. As of Mar 16th 2020, 165 000 cases and 6 500 deaths have been reported over 146 countries (WHO data). In Europe, Italy, Spain, France and Germany are currently
Immune response during Covid19 infection – CovImmune
Since March 2020, Europe has been facing the outbreak of the new coronavirus disease 2019 (COVID-19). This highly contagious infectious disease is a viral zoonosis caused by a virus SARS-CoV-2 from the coronavirus family that emerged in Wuhan in Chine in November 2019, causing first an epidemic that