Process optimisation by flow chemistry and experimental design – OPTIFLEX

The objective of the OPTIFLEX project is to develop an original methodology for model-based experimental design, exploiting information from flow chemistry and pilot reactors in order to optimize the operating conditions of synthesis reactors. The challenge is to accelerate the first steps at the laboratory and small pilot stage by reducing study times, the number of experimental tests and the associated costs. This methodology will implement two complementary experimental platforms (automatic flow chemistry and pilot reactors in semi-manual mode) controlled by computer programs. The preliminary phase concerns the acquisition of information which is characteristic of the reaction system (operating range, selectivity, yield, stoichiometric reaction scheme) in order to search for the optimal synthesis conditions in a second step.