Modelling Zoonotic Arthropod-borne pathogens: “One Health” modelling to studying the drivers of Lyme borreliosis & tick-borne encephalitis incidence – MoZArt

Vector-borne diseases are an increasing global health threat, displaying complex epidemiological cycles at the interface between animals, vectors and humans. Lyme borreliosis (LB) and tick-borne encephalitis (TBE) are tick-borne zoonoses of growing public health concern in temperate regions of the world. LB and TBE are transmitted by the same tick Ixodes ricinus, thus offering a unique opportunity to study them jointly in the same study area. In particular, the relative importance of animals, vectors, environment and humans in shaping disease incidence has yet to be quantified in a single framework, to formally assist disease prevention and control. By jointly analysing uniquely well documented ‘One Health’ datasets on both diseases in France with state-of-the-art modelling techniques, we will simultaneously shed light on their epidemiological and public health features; whilst paving the way for the next generation of models to assist tick-borne zoonoses prevention and control.