Shape-learning 3D DNA Nanostructures and self-replicative ability – NanoShapeLearn
Our understanding of DNA has advanced to a level that allows us to start building sophisticated 3D-nanostructures using DNA as a construction material. Recently, a quantum leap of complexity has been achieved by using DNA origami and DNA Lego methods creating fully addressable three-dimensional DNA nanostructures designed on densely packed lattices. However, a number of critical challenges limit their potential for practical applications. Here, revisiting the original design framework, we propose a new nano-manufacturing paradigm that circumvents the sophisticated in silico design, low-scale production and size limitations intrinsic to the current DNA self-assembly methods.
Project coordination
Gaëtan BELLOT (Centre de Biochimie Structurale)
The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.
Partnership
GULLIVER
LIMMS Laboratory for Integrated Micro Mechatronics Systems
LIP Centre national de la recherche scientifique
CBS Centre de Biochimie Structurale
Help of the ANR 508,728 euros
Beginning and duration of the scientific project:
March 2023
- 48 Months
