Personalized virtual transcatheter aortic valve assessment – AorticVirtu_et_al

Valve thrombosis is a recent discovery for which it can be suspected that changes in local hemodynamics associated with implantation of the valve after TAVR stand as a contributing factor. No independent studies are currently published on changes in aortic hemodynamics after TAVR depending on the patient's aortic anatomy, valve type and size. The objective of this personalized medicine project is to develop an accurate virtual aortic surgery platform to assist the surgeon/doctor as a necessary aid to decision-making and reduction of postoperative risks. One of the main difficulties in this process is the accurate simulation of the blood-valve coupled interactions, which remains very challenging. Innovative simulation techniques based on the SPH and the LBM methods will be used to that aim. As inputs of the model, accurate patient anatomy measurements and careful biomechanical properties assessment of the patient tissues and valves will be also required.