JCJC - Jeunes chercheuses & jeunes chercheurs

Synthèse de Radioligands pour l'Imagerie Médicale. Applications au récepteur 5-HT7. – SyRIM

Submission summary

With the development of PET = positron emission tomography (or as it is more appropriate to denote it PET = positron emission tracer technique) as a general in vivo tracer method, the opportunity has opened up to perform non-perturbated observations in vivo both in research animals and in humans. PET is an imaging technique that is able to detect positron-emitters within an animal or human body. Carbon 11 and fluorine 18 are positron-emitters that can be incorporated into drug molecules to provide biochemically radiopharmaceuticals, including ligands for neurotransmitter receptors. - These measurements can be performed at much lower drug concentrations than previously been possible, allowing various evaluations of distribution and pharmacological interventions with pharmacologically inactive tracer doses and combining information from non-perturbated systems - ...

Project coordination

Thierry BILLARD (Université)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.

Partner

Help of the ANR 190,000 euros
Beginning and duration of the scientific project: - 48 Months

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