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Emergence and maintenance of neuronal function and behavior in the fly: from embryonic scenes through larval and adult stages to dysfunctions – EmFly
Long-term maintenance of neuronal function is critical to preserve an animal’s behaviour throughout its life. How is this achieved during developmental stages and in pathological conditions? I will study the mechanisms of this maintenance in the nervous system of the fruit fly, Drosophila melanogast
Recombination and Epistasis at the Genome level, extant, molecular bases and implication on clone emergence in Escherichia coli – EcoRecEp
The spread of antibiotic resistance has clearly illustrated the need for an evolutionary approach to study infectious diseases. With the advent of genomics, molecular epidemiology clusters strains according to their genetic characteristics and looks for associations between these groups and variable
ENERgy driven modelling of tissue architecture emerGENCE and homeorhesis – ENERGENCE
With the increase in life expectancy in most countries, understanding the mechanisms of tissue decline has become a major public health priority for our society. Decline of tissue functions is correlated with a loss of its architecture. The emergence of this architecture and subsequent maintenance
Digital Twin for an Emergency Department – JUNEAU
The Emergency Department (ED) represents the first stage of the path for some patients in a Hospital (UH). This project aims to propose a Digital Twin (DT) for the ED to both visualise the service behaviour in quasi real-time and forecast and anticipate its behaviour to control the “Emergency throug
mRNA vaccines for fast responses to fish emergent infectious diseases in a context of global climate change – FishRNATherm
Environmental changes linked to global warming imposes new challenges on aquaculture, in particular through emerging infectious diseases. Fast production of effective vaccines, particularly against viruses, is therefore essential for sustainable aquaculture, in order to prevent infectious diseases t
The role of sleep disturbances in the emergence of neuropsychiatric symptoms in aging and neurodegenerative diseases – SENPSY
It is estimated that around 139 million individuals will suffer from dementia worldwide by 2050, with Alzheimer’s disease (AD) and dementia with Lewy Bodies (DLB) being the leading causes. No curative nor preventive treatment is yet available, although disease-modifying therapies for AD do offer som
Spatial multi-omics by high-resolution mass spectrometry for the comprehensive evaluation of emerging contaminants toxicity in freshwater sentinel species – SPECTRUM
Metabolic syndrome has led to an increased use of type 2 diabetes (T2D) medications, such as metformin, GLP-1 receptor agonists, and SGLT2 inhibitors. These medications have become environmental contaminants due to their presence in wastewater and drinking water. Their widespread occurrence and ecot
Disease EMergence in an isolated Environment : understanding Transmission to control Epidemics in Rice – DEMETERice
Disease outbreaks are a major threat to humans, animals and plants. In the absence of treatments, vaccines or resistant varieties, preventing the transmission of pathogens appears to be the main alternative to control their spread, limit their impact and to prevent new introductions. Rice is one of
Emergence of Viral Diseases Challenging Sustainability of Aquaculture: Novirhabdovirus Adaptation to Climate Change – ThermoFish
The control and management of infectious diseases that affect aquaculture fish are major challenges for improving animal and human health. Climate change raises the critical question of the adaptation of pathogens to rising temperatures. While the importation of tropical pathogens into our latitudes
Acheulean roots: the emergence and early developments of the oldest complex material culture – AcheuleanRoots
AcheuleanRoots is an international and interdisciplinary project that investigates the behavioral innovations that accompanied the emergence and early development of the Acheulean, the earliest complex material culture in prehistory. Focusing on technological and subsistence strategies, the project
