Search
Cannabinod receptor 1 inhibition for Treating ciliopathies – CaRTCil
Chronic kidney disease (CKD) is a major public health concern, affecting millions worldwide. Ciliopathies such as ADPKD, ARPKD, and nephronophthisis are genetic disorders that disrupt primary cilium function, leading to cyst formation and renal fibrosis. Current treatments offer limited efficacy in
Cannabinoid receptors in cortical visual encoding – CaCoVi
In the neocortex, sensory-evoked activity is sculpted by synaptic inhibition originating from a rich diversity of GABAergic interneurons. In particular, cholecystokinin (CCK)-positive basket cells are a prominent type of perisomatic targeting interneurons, whose synaptic plasticity relies on their h
Capillary flows of suspensions – POLYSHAPE
Polyphasic liquids (suspensions, emulsions, wetted foams) are ubiquitous in nature and industry (soils, pulps, pastes…). As for conventional liquids, there is an increasing need to optimize capillary flows of these liquids at smaller and smaller scales, with concern to both the overall polyphasic en
Capitalizing knowledge on Common Alerting Protocol, individual Capacities & Capabilities of practitioners for guiding a New Cap for Alerting population in France with a multichannel platform. – Cap-4-Multi-Can-Alert
This project was created in response to assess two shortcomings: 1) the lack of efficiency and clarity in the contents of the warning tools in France (a sound signal for the sirens of the SAIP network, a voice/text message for the automatic warning systems, a text message for the geolocated SMS and
Captialization of working time: collective bargaining and usages in France and Germany – CATT
This comparative research project handles new forms of individual and collective works’ organizations generated by the development of negotiated capitalization’ mechanisms in France and in Germany. It seeks to shed new light on a widespread social phenomenon yet little studied in France. In the fram
Carb2zyme: Unprecedented chemistry for carbon-carbon bond formation by an emerging class of metallo-enzymes – Carb2zyme
Carbon-carbon bond formation plays an important role in the chemical industry. However, only few methodologies are available for C–C bond formation at unreactive carbon atoms. These methods often require noble metals and stringent experimental conditions which are not compatible with green chemistry
Carbene-catalyzed super-reductions through direct photoactivation of intermediates – CASPI
The ultimate goal of the CASPI project is the rational design of extremely-reductive processes with N-Heterocyclic Carbene (NHC) organocatalysis through direct light-activation of already reductive catalytic intermediates. The proposal is based on the emerging concepts, such as ConPET (Consecutive
Carbohydrate cOnjugates as Trojan horsE to improve Antibiotic iMport – CO-TEAM
The increase of antimicrobial resistance is a major threat for individual and public health. Consequently, new weapons to fight the emerging multidrug-resistant bacteria are quickly required. The ESKAPE pathogens are at the frontline of these problematic life-threatening drug resistant nosocomial pa
Carbon and Sulfur Isotopic fractionation during Planetary differentiation – CSI-Planet
This project aims to understand the origin of the differences in carbon and sulfur contents and isotopic signatures between Earth and Mars. Thanks to an experimental approach, this project will determine C and S partitioning and isotopic fractionation during planetary core formation and during the
Cartographie Numérique des Sols par imagerie hyperspectrale pour la modélisation environnementale en région méditerranéenne – DIGISOL-HYMED
To be fully operational for assisting decisions at global, national and local levels, environmental modelling require precise spatially referenced soil information as inputs. The current soil database that exist in the world are neither exhaustive nor precise enough for being used efficiently for th