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Structural, dynamic and functional approach of the Hsp90 chaperone machinery: exploration by conformational probes – MACHsp90
In September 2007 in its weekly epidemiological bulletin the Institut National de Veille Sanitaire (INVS) as announced that for the first time in France, cancer is the leading cause of death before cardiovascular diseases. Indeed, cancer incidence as doubled between 1980 and 2005. Therefore, the dev
La mixité des formes organisationnelles au sein des réseaux de franchise, ses antécédents et ses conséquences en termes de management et de performance – FRANMIX
Franchising is widely used in most countries of the world, developed ones and emerging ones. France occupies a strong position at the European level and also at the international level. The latest figures provided by the French Federation of Franchising indicate that there were 1,037 franchising net
Laser Spectrometer for Stellar Astrophysics – LASSA
This project began as a collaborative investigation between P. Crozet (LASIM) and J-F Donati (LATT) initiated in the framework of the Programme Nationale de Physique Stellaire (PNPS) in 2007, aiming to address the laboratory requirements of stellar astrophysics, and in particular of stellar polarime
Demonstrateur d'élément modulaire de caméra pour CTA – NeCTAr
The high energy gamma ray astronomy is a new emerging field of astroparticle physics. It detects gamma rays with energy in the range 10 GeV-100 TeV. The best results have been obtained with small arrays of ground-based Cherenkov telescopes. The most advanced example is the H.E.S.S. array, which ha
Hematopoietic progenitors in Drosophila. Micro-environment and fate studies in normal and following parasitism. – prohemodroso
Background: The innate immune response confers all multicellular organisms broad protection against pathogens. Drosophila has become a major model organism to study hematopoiesis and cellular aspects of the innate immune response. As in vertebrates, Drosophila hematopoiesis occurs in two phases. A f
INHIBITION SÉLÉCTIVE DES INTÉRACTIONS PROTÉINE-PROTÉINE: LES DOMAINES PDZ IMPLIQUÉS DANS LE CANCER ET LA DOULEUR NEUROPATHIQUE – PDZ-CANPAIN
In 2007, the FDA approved only 17 new drugs, of which 4 were indicated in the treatment of cancer and 2 for the treatment of CNS-related diseases. Beside increased levels of regulatory caution, the scarcity of new drugs also results from the lack of novel targets. To overcome this target shortage, s
Dual Bell Nozzle Optimization (DBNO) – DBNO
Control of flow regime transition and integrated control – thrust vectoring system via secondary fluidic transverse injection in a dual-bell rocket nozzle To expand the combusted gas products in order to obtain the ideal propulsive thrust ratio, the exhaust nozzle should be adapted to the external
Characterization of cerebral and oculometric markers of the out-of-the-loop phenomenon during the supervision of an automated system in aeronautic context – EMOOL
In recent decades, the world around us has experienced profound technological changes, driven in particular by advances in autonomy, robotics and artificial intelligence. Today, human agents are regularly confronted highly automated, even autonomous systems, whose the primary role is to supervise th
