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Integration of computational modelling with transcription and gene essentiality profiling of both MTB bacillus and infected human dendritic cells and macrophages to understand molecular interaction networks involved in the host pathogen cross-talk – ERASYSBIO (ANR-09-SYSB-0005)
Mycobacterium tuberculosis is a major pathogen of man. Drug treatment is available for human disease but it takes six months, which is impractical in developing world settings where TB is most common. Consequent non-compliance with treatment regimes leads to the emergence of drug resistance. This is
One-pot selective amination of GLYcerol using ligand decorated metal NANOparticles – GLYNANO
Despite considerable efforts, the transformation of biomass products into valuable nitrogen-containing chemicals still represents an important challenge today. Yet, their demand is dramatically increasing worldwide, since amines are sought for their unique properties as corrosion inhibitors, paints
Secure V – SecV
For decades, processors evolution has focused on improving their performance. In recent years, attacks directly exploiting optimization mechanisms have emerged. They typically exploit flaws in caches, performance counters or speculation units and jeopardize the safety and security of processors in
Emergency reorganisation and improvisation in crisis management – RESCUE
In France, industrial sites with high technological risks have the obligation to carry out a crisis management planning which describes the means, equipment and methods of intervention. However, during an industrial disaster, this planning may prove to be unsuitable and operational personnel must ur
From fantasies to problematic sexual behavior and sexual violence in youth aged 18 to 25 – FRIDA
Paraphilic sexual fantasies are an undeniable risk factor of sexual violence (e.g. fantasies of domination or sadism in the case of rape). However, it is difficult to distinguish between normophilic and paraphilic fantasies, and it is not just their content that poses a problem amongst sexual offend
How to build new eco-designed biotransformation routes ? – NewEco-Routes
To be sustainable, bioeconomy development must integrate environmental, social and economic issues. The use of biotechnological processes is promising for producing value-added molecules from various renewable biomass resources and by-products. Relevant and efficient combinations of unit operations
Blood-brain barrier crossing of conventional and new antidotes to treat organophosphate poisoning. – BHE-OP-Antidotes
Organophosphates (OPs) constitute a class of synthetic molecules still widely used as an insecticide but also as chemical weapons. This class has been the subject of numerous investigations by the chemical industry in search of pesticides that are more effective and potentially less harmful to the e
The role of linguistic and non-linguistic factors in the evolution of nominal classification systems – EVOGRAM
Categorization is one the most frequent tasks realized by humans during their life, as elements and experience encountered need to be categorized to be efficiently stored and retrieved within the human brain. Such need is reflected in language via various mechanisms such as grammatical gender (e.g.,
Efficient reverse design of green solvents for emerging solution-processed photovoltaic technologies – GreenPHOTOSOLV
Within the context of a fast growing demand of renewable electrical energy, GreenPHOTOSOLV project deals with current development challenges of printed photovoltaic technologies through the novel application of a systemic approach based on reverse engineering. The project addresses two major issues
Luminescent materials for broadband bright new light sources – Newlight
An LED-pumped luminescent concentrator (LC) is a parallelepiped-shaped luminescent material with LEDs on its large sides. After absorbing light from the LEDs, the material re-emits light into the LC which is guided to its edges. Concentration is achieved through total internal reflections. This lead
