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Experimental investigation and modelling of strain-induced crystallisation in natural rubber in different ageing conditions
Strain-induced crystallisation (SIC) in natural rubber is at the origin of its outstanding performances such as self-reinforcement and resistance to failure. The SICX project has several objectives: First, it aims to provide a comprehensive set of data describing the kinetic evolution of the microst
MechAnical prOPerties of Lipid Layers dOped with microparticles
Lipid monolayers such as lung surfactants or the outer layer of the tear film control crucial organ activities. Even though they are frequently exposed to micropollutants, the fundamental mechanism behind the adsorption of microparticles at lipid laden interfaces and its effect on the macroscopic m
poly(triméthylèneCarbonate) - development of tailorable ecofriendly antifouling coatings
The protection of immersed surfaces in the marine environment is a major economic, societal and environmental issue. All immersed surfaces undergo spontaneous biocolonisation. The consequences of this development onto surfaces are catastrophic. The main objectives of the scientific community are to
Development, Evaluation and Simulation of ARC Defect Resistant Materials
The electrification of transport implies a strong increase in power and voltage in on-board networks (particularly in aeronautics). The risk of damages due to arcing faults is thus increased. The arc fault is unavoidable, so it must be detected. The arc detection involves a minimum delay during whic
Tri-segmented side-chain conjugated polymers for fine-tuning the performance of doped organic electronics
The project TriPODE aims at providing a breakthrough in the field of doped polymeric systems through a strategy of side-chain engineering of conjugated semiconducting polymers to fine-tune the performance of doped organic electronics. Two applications are targeted in particular: thermoelectricity de
Harvesting Elemental Sulfur as Landfill Waste Towards Novel Polymers by Design
Polymers are truly shaping today’s world and can be found everywhere, from commodity plastics to high-end technologies. As chemists, this raises an important question: Can we make plastics more sustainable by using resources that can act as an alternative to the current fossil-based solutions, and t
Precise pore-forming assemblies of bioinspired foldamers for selective water translocation
The design and precise construction of biomimetic self-assembling folded systems in aqueous conditions is a challenging yet potentially highly rewarding endeavor, contributing to the development of new biomaterials, catalysts, drug-delivery systems and tools for the manipulation of biological proces
Sustainable Process Design for Catalytic Polymerization to In-Chain Functionalized Polyethylenes
Polyethylene is the largest produced plastic material, used in many key technology areas. Its production efficiency is superior to most other plastics in terms of environmental impact. The linear hydrocarbon chains of polyethylene (HDPE) enable crystalline packing and provide excellent mechanical p
Arresting Bubble Coarsening: Gelling from Liquid to Solid Foams
The properties of aqueous foams are largely dictated by capillary effects as surface forces dominate their structure, ageing and rheology. The solidification of the continuous phase takes us into the world of solid mechanics with fixed structures, and very different evolution and mechanical properti
Light-Emitting Multifunctional Polymers for Organic Lasers and Laser Diodes
The first demonstration of electrically-pumped Organic Laser Diode OLD, based on an evaporated single blue emitter layer, has been recently demonstrated (2019). This very important breakthrough will lead to a new class of extremely compact, cheap and flexible lasers with broad industrial application
3D printed hybrid degradable networks combining polymers and virus like particles through spytag-spycatcher ligation
Bioactive materials are a cornerstone of modern medicine for medical devices (MD) or scaffolds for tissue engineering (TE). They should combine tunable mechanical properties, biofunctionality through spatially localized biomolecules, compatibility with 3D printing and degradability. In particular fo
HIgh Performance nanostructured POlymer networks using POlymerizaTion-induced self-Assembly in reactive MEdia
HIPPOPOTAME aims at establishing simple and general routes to design industrially-relevant thermosets with extended lifetime through mechanical reinforcement induced by organization of block copolymers as vesicles and more particularly as wormlike micelles in epoxy networks. To do so, HIPPOPOTAME wi
Two-Photon Polymerization of Ruthenium-based Materials: a Microfabrication Platform for Electrochemiluminescent Multiplexing Sensors.
The proposed project aims in elaborating an original ‘one pot’ two-photon polymerisation process for the photostructuration of Ruthenium-based materials devoted to the fabrication of electrochemilumiscent (ECL) multiplexing immunosensors at µm scale. This original approach takes benefit of recent te
Fe-catalyzed chain shuttling polymerization of ethylene and 1,3-diene
The FEATHER project aims to prepare unprecedented multiblock copolymers (MBCPs) composed of multiple repetitions of linear ethylene blocks and 1,3-diene blocks, resulting in innovative thermoplastic elastomers (TPE). To achieve this goal, a chain shuttling polymerization (CSP) process will be implem
Photoswitchable glycomacrocycles as chiral dopants for liquid crystals and fabrication of microswimmers
The recent discovery that some photochromic glycomacrocycles could substitute for “molecular motors” in the development of photoactive cholesteric liquid crystals (CLCs) opens up a huge field of research due to the great variability of natural glycosides, the infinite potentialities of substitutions
Ultrasound-triggered disruption and self-healing of hydrogels for on-demand and repeated cargo release
Injectable hydrogels that allow remote, repeatable, and controlled on-off switchable drug release could have a marked impact on the treatment of a variety of medical conditions. An ideal hydrogel should safely contain a large quantity of drug, release no drug in the “off” state, be repeatedly switch
Gels of Edibles Oils by Endogenous Fatty Amides
Saturated fatty acids (SFA) and trans-Fatty acids (TFA) and are a major public health issue because they increase the risks of cardiovascular diseases. TFA and SFA are found mainly in solid fats, and form crystalline triacylglycerol. This crystallinity plays an essential role to texture the lipid ph
Core-shell Nanofibers with Tunable Dimensions and Mechanics for Targeting Immune Cells in the Intestine
Oral vaccination offers great potential since it does not require trained personal, avoids the use of needles, and improves compliance of patient. However, vaccination through mucosal routes remains a great challenge. It suffers from low efficiency because the antigens face several severe hurdles by
Efficient chiral separation using electrospun cellulosic membranes
Many compounds of biological interest such as amino acids and drugs have chiral structures on which rely their physiological properties. Hence, chiral separation is crucial and resolution of racemates by High Performance Liquid Chromatography (HPLC) equipped with polysaccharides-based chiral columns
Process for the synthesis of lipid nanoparticles encapsulating polynucleotides
The delivery of polynucleotides such as messenger RNA is now industrialized via vectorization in lipid nanoparticles. These nano-objects are nanocomposites in which the mRNA is condensed by complexation with a cationic lipid and coated with a shell of phospholipids and cholesterol. Their synthesis i
Dynamics of chiral guest-host systems
Motivated by recent and engaging results showing the fundamental role of chirality in the dynamic of soft matter systems and the technological need of the pharmaceutical industry for chiral differentiation, the CHIRALGHOST research project proposes to examine new possibilities of achieving the separ
Making Soft Solids by Shear-assisted Assembly of Colloids
Numerous hard materials from major industries, i.e., foodstuff, personal care, and building materials, are obtained from soft viscoelastic precursors. In practice, controlling the properties of these soft precursors is critical to control the terminal properties of the corresponding hardened materia
Directing FOAM structures with INTruders: self-assembly of architected materials via elasto-capillarity
Architected materials are attracting a growing interest: structural design results in intriguing features that drastically differ from that of the bulk materials, with a combination of light weight and interesting mechanical, acoustic, electrical or thermal properties. Beyond rapid prototyping and 3
Electrically-driven solitons in nematic liquid crystals
Solitons in nematic liquid crystals (NLCs) are self-confined perturbations of orientation of their elongated molecules. Robust to perturbations, solitons can propagate long distances without distortion. Besides simple collisions, they can interact between each-other and with their surrounding in a p
Saliva Composition, Aerosolization and DRying Impact on Viral transmission
Aerosols exchanged between asymptomatic carriers are the most significant transmission route for the SARS-CoV-2 virus, responsible for the COVID-19 pandemic. But successful transmission depends on the maintenance of viral infectivity during aerial transport. Understanding the coupling between the bi
Photo-Induced Carbonate-Amine Polyaddition for the On-Demand Synthesis of Non-Isocyanate Polyurethanes
Photopolymerization is one of the most promising technologies for the advanced manufacturing of polymers. It is a flexible method meeting the latest demands of Industry 4.0, notably with the breakthrough of 3D-printing by stereolithography (SLA). If the field has long been dominated by radical chemi
Biocompatible Porous Liquids based on Cyclodextrin-MOFs and eutectic solvents
The aim of the CDeePL project is to design new biocompatible Porous Liquids (PLs) able of selectively dissolving target molecules. These innovative materials will be obtained by dispersing Cyclodextrin-Metal-Organic Frameworks (CD-MOFs) in Deep Eutectic Solvents (DESs). The use of biocompatible star
Vinyl Polymers End-of-life: Recycling/Composting
Organic materials (or plastics) occupy an important place in our society. Due to the large choice of polymers produced and the multiple properties available (in terms of mechanical, thermal or solubilization behavior), they have become indispensable in everyday life as well as in the industrial worl
Self-PrOPelled ARTificial protocells
Mimicking the properties of life in artificial cells is a current research frontier in synthetic biology. Among the many properties of artificial cells that aim to mimic metabolism, growth, sensing, etc., reproducing motility and directional swimming is major for understanding the individual and col
Cell-MIMEtic soft active SYStems
Bioinspired microdevices are the prelude to a great advance in biomedical technologies. However, there is a clear gap in fabricating prototypes of the size and complexity of cells. Active colloids are an experimental paradigm to realize microrobots due to their ability to self-propel and perform sim
Emissive mechanoresponsive hybrid Poly(urethane)
Direct translation of mechanical force into an easy to read luminescent signal opens a new realm of possibilities in the field of mechanical stress sensing. To date, the development of such functional materials relies mostly on organic emissive mechanophores and has been hampered by photobleaching,
Tailored polyhydroxyalcanoates to tune medical device bioresorption
The objective of the PHAMOUS project is the diversification and optimization of the biosynthesis of original polyhydroxyalkanoates (PHA) and their valorization in healthcare applications for the development of innovative medical devices. To achieve these objectives, the PHAMOUS project will gather t
Novel Structural Color Materials from Self-Assembly of Biosourced Brush-like Copolymers
Colored structural materials found in nature are of great interest and their fascinating properties have stimulated the design of bioinspired functional photonic materials. Due to their intrinsic ability to modify the propagation of visible light, they are potential candidates for various optoelectr
Acylated Acetals: A Chemical Platform for Advanced Covalent Adaptable Networks and Isoporous Functional Membranes
Acylated acetals (AcAc, also known as hemiacetal esters) and hybrid AcAc constitute a very interesting class of compounds which have been largely underused and understudied. They can be seen as a subclass of acetals in which one of the constitutive RO– group is replaced by an ester (RCOO–). The vast
Dynamically Crosslinked Nanostructured Elastomers
With the increased dependency of our society on plastic-based materials, the recycling of plastics has become a crucial challenge. An interesting class of recyclable polymers is thermoplastic elastomers (TPE). These polymers are usually constituted of incompatible soft and hard blocks copolymers tha
Copper radical reactivity: pushing the frontiers of atom transfer radical polymerization
Since its discovery in 1995, atom transfer radical polymerization (ATRP) has drawn the keen attention of both academic and industrial researchers because of its revolutionary perspectives in terms of new advanced materials synthesis. This is a metal-catalyzed process, the most efficient catalysts be