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Structure-function relationships of Ferric Uptake Regulators and their inhibitors: towards new peptido-siderophore antibacterial compounds – PepSiFUR
Iron homeostasis and virulence of pathogens are intimately linked. A key actor of this metabolism in bacteria is the Fur protein (Ferric uptake regulator), a global transcriptional regulator of the expression of the genes involved in iron homeostasis. Any perturbation of Fur activity will affect pro
Clathrates hydrates with H-bond defects for hydrogen storage – HyDfect
The natural existence of large quantities of hydrocarbon hydrates in deep oceans and permafrost is probably at the origin of numerous applications in the broad areas of energy and environmental sciences. At a fundamental level, the peculiar nanostructuration of clathrate hydrates confers on these ma
Design of new high voltage SuperJunction power switches – SUPER SWITCH
The objective of this project is to fabricate Deep Trench SuperJunction power devices (diodes and MOSFETs) in the 600-1200 Volts voltage range. Deep vertical etchings were obtained by ICP-DRIE at LAAS and by electrochemistry at GREMAN. PIII implantations were performed on top wafer at IBS: it remain
Understanding and optimization of local electrografting – COPEL
Organic coatings on surfaces are present everywhere in today’s life, from paints used in car industry to medical devices. Among the different coating techniques, electrografting which is based on the electro-induced polymerization of dissolved electro-active monomers on metallic or semiconducting su
Multimodal quantification and validation of 3D regional myocardial function – 3DSTRAIN
The 3DSTRAIN project was submitted last year under the acronym VSTRAIN3D. The main issues reported by the reviewers and the evaluation committee, have been addressed: need for the adaptation of the proposed algorithm to each modality, poor involvement of the industrial partner, evaluation process to
Multi-scale modeling of ion transport in nanofiltration – MUTINA
Although nanofiltration (NF) has attracted increasing attention over the recent years, its current industrial applications are still limited compared to the great potentialities of this separation process. The major reason is that the physical phenomena involved in the separation process by nanoporo
Multi-functional memory elements using supramolecular self constructing interconnects – MultiSelf
The field of organic electronics is of growing importance, in particular for portable electronics, as well as low power and cheap electronics applications. Improving the conductivity of materials, as well as the interface between organic components and metallic interconnects are major problems, key
Development of stainless steel microbial cathodes for microbial fuel cells – BioCathInox
The “Laboratoire de Génie Chimique” has made a decisive answer to the problem of the cathode. This innovation on the cathodic process could be the solution to saving MFC technology. However locks persist and scientific knowledge on fundamental processes are not yet understood. The final objective is
Modelling charge transport in solid dielectrics under electrical stresses and implication on materials reliability in electrical engineering – ModElec
The main objectives of this project are as follow: - The development of a transport model including physical mechanisms like polarization, recombination and diffusion; - The understanding of the conditions where some particular phenomena are observed experimentally - The validation of the transpo
High energy efficiency heat pumps for relectrified vehicles and trains – ELEC-HP
The ELEC-HP project aims at developing a family of automotive heat pumps to be sustituted to heating by electric resistances. Barriers to overcome are as follows: - use a refrigerant with a GWP < 150, which presents good energy efficiency in heating for -20 °C outdoor temperature and in cooling