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Functional and structural studies of TSSP, a novel serine protease that diversify the functional CD4 T cell repertoire and controls spontaneous autoimmune diabetes in NOD mice – TSSP
TSSP is a new protease that controls by yet unknown mechanisms the development of self-reactive T cells directly involved in the development of autoimmune diabetes. The main objective of this project are to elucidate TSSP function and finds potential substrates. Beside fundamental knowledge in the
Rockfall risk: the use of Artificial Intelligence for the operational management of the risk – C2R-IA
Currently, the management of rockfall risk is mainly dealt with the construction of protective structures, which often represents a disproportionate cost compared to the financial resources of municipalities and private operators. Morever, it is often impossible to develop such solutions over an ent
Asian monsoon Tropical Tropopause Layer: transport and composition – TTL-Xing
Our project will considerably increase understanding of key processes that governs the large-scale impact of the Asian monsoon and increase our ability to manage anthropogenic changes. It is built on the rapidly improving situation on the observation side, on recent modeling developments and on the
Digital Materials - An industrial Reality In Motion – RealIMotion
One of the European Union's climate change objectives is to achieve net-zero greenhouse gas emissions by 2050. This goal puts significant pressure on the metallic materials industry, a major contributor to fossil CO2 emissions, necessitating powerful digital strategies to design, improve, and calibr
Prediction of cerebral injury secondary to endovascular recanalization of acute ischemic stroke – PRECISE-STROKE
Acute Brain Infarction complicating large vessel occlusion (LVO-AIS) are one of the first causes of neurological dependency and death in Europe. Their incidence is expected to increase by 20% in the next 10 years. Endovascular recanalisation (EVT) has revolutionized their management. It was initiall
Multiscale Sensing For Disease Monitoring In Vineyard Production – MERIAVINO
The Meriavino project aims to help winegrowers access real-time information and diagnostics to make agronomic decisions. The aim is to improve monitoring processes using multi-scale remote sensing and Internet of Things (IoT) devices, on interconnected vineyard plots, with a non-invasive, eco-friend
Explainable artificial intelligence for anti-money laundering – XAIforAML
Financial institutions and government authorities want to introduce more advanced AI tools in AML-CFT processes. Financial institutions see AI as a way to reduce costs. Regulators see AI as a way to identify more criminal networks that currently escape prosecution (the director of Europol estimates
Social Networks for Natural Disaster: Operational Interpretation – ReSoCIO
Two-thirds of French municipalities are considered to be exposed to natural disasters. Flooding is the most frequent risk, while seismic risk is among the most feared in terms of potential victims. This situation is likely to worsen in the coming decades, due to the combination of an increase in the
