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The Starch Food Niche: Human Adaptation, Genes and Culture – Starch4Sapiens
Starch4Sapiens aims to analyze and compare the biological and behavioral changes that made possible efficient starchy food metabolization which occurred in Eurasia between the Upper Pleistocene and Neolithic (from ca 126 ka to 12 ka, 6). Our hypothesis is that regular consumption of large amounts of
Impact of tailings on Environment: example of transfers of elements from Spoil tips in the North of France – ENTRESOL
Since the beginnings of the industrial period, the exploitation of the underground resources has been constantly expanding, in line with the ever-increasing demand of mankind to satisfy their needs and comfort. This exploitation of the subsoil has strong impacts on the environment notably with the g
EcoHealth approach for the evaluation of SDHI fungicides use: exposome and hazards for biodiversity and human health – SoEcohealth
The catalytic region of the SDH is highly conserved across species: SDHI target mitochondrial functions that are not only critical in agricultural fungi, but also in all animals and plant species that have mitochondria. With respect to human health, genetic diseases and cancer genetics provide evide
INSIGHTS INTO SOCIAL EXCLUSION RESPONSES: THE COGNITIVE UNDERPINNINGS OF ANTI- AND PRO-SOCIAL BEHAVIORS – InSER
In Task 1, we will examine early cognitive and affective responses to social exclusion. We anticipate that the prioritization of early anti- vs. prosocial responses depends on initial situational appraisals. Specifically, after exclusion, the prospect for consecutive exclusion facilitates cognitive
Straightforward access to enantiopure NHC-Transition Metal Complexes: New opportunities for asymmetric catalysis – cResolu
The goals of this project are the development of an original design of chiral carbene ligands. In sharp contrast with the literature, the concept which will be developed does not lie neither on the introduction of chiral moieties as N-substituents nor on the use of stereogenic center(s) on cylic car
Digital twin contribution to better control the morphological properties of aggregates under hydrodynamic constraints – MORPHING
The MORPHING project is part of a perspective of developing generic tools aiming at allowing a fundamental advance in the understanding of aggregation phenomena in suspension. The aggregation of latex nanoparticles with a butadiene core in an industrial stirred reactor is a case study. The scientifi
To capitalize on activated adventitial fibroblasts metabolism to treat pulmonary hypertension – Gly-Pro-PH
Vascular stiffness and extracellular matrix (ECM) remodelling promote pulmonary vascular dysfunction early in PH pathogenesis. Although anatomic location may dictate distinct effects on disease progression, stiffness in both the proximal and distal pulmonary arterial tree is important for overall pa
Deciphering the gene regulatory network logic underlying whole-body regeneration – RENEW
Our overall objective is to determine the regulatory networks triggered by an injury and that initiate a whole-body regenerative response by dissecting the 1) transcriptional dynamics and 2) genome-wide chromatin accessibility at the tissue and single-cell levels, in order to 3) infer and 4) validat
Sodium channel trafficking pathways in cardiomyocyte – TRAFFIC
The cardiomyocyte is composed of distinct anatomical and functional domains. The costamere provides the link between the extracellular matrix and the sarcomere along the cardiomyocyte1. The intercalated disc connects the endings of adjacent cardiomyocytes. It comprises various complexes: fascia adhe
Towards Industrialisation of Direct Liquid Injection CVD Process for Alkaline Niobate Thin Films – LINKS
These developments could open new possibilities of further miniaturization and the integration of next-generation MEMS, acoustic rf filters, ferroelectronic, and nanophotonic devices (ex. for 5G applications). The fabrication of high-quality alkaline niobate films at industrial scale is hindered by
