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Origins of the specialization for reading in the occipitotemporal cortex – TOPLEX
Reading and writing constitute a major invention on which most modern culture is predicated. Understanding how the visual system adapts to the novel, culture-dependent task of identifying written words represents a formidable case study of brain plasticity, at the convergence of psychology, neurosci
Origins of divergence – The causes of pre- and post-zygotic isolation barriers in Spodoptera frugiperda – ORIGINS
The objectives of the project are: 1) Unambiguous identification and characterization of diverging genetic loci between the strains. Using a new population genomics approach, all loci diverging between the strains will be identified. The identified genetic variants will be classified according to
Original Scalable Quantum Mechanical Strategies to Refine High-Resolution Crystallographic Structures of Macromolecules – QuMacroRef
The main goal of the project is to propose a new set of fast computational tools in order to routinely refine crystal structures and electron densities of macromolecules (particularly proteins) when sub-atomic (d = 1.0 Å) or ultra-high (d = 0.7 Å) resolution X-ray diffraction data are available. Thi
Origin and function of the pituitary generator of GH pulses – GH-Gen
A current challenge in physiology/pathology is translating cell-transduction processes identified in vitro into the living organism, especially where cell-cell interaction and dynamics have key functional roles. The pituitary gland, regulating a range of essential physiological functions, exemplifie
Origami-based structures for multi-modal Robots – OrigaBot
The OrigaBot project aims to develop an innovative mobile robot based on a new family of origami structures for robots with a flexible mechanical structure that is active, reconfigurable and deformable. The OrigaBot will be a multimodal locomotion mobile robot with a reconfigurable structure to roll
Organolanthanide complexes with slow magnetic relaxation – RelaxMax
The objective of the project is to make high-performance molecular magnets from organometallic compounds of lanthanides. In particular, we are interested in compounds of the sandwich type with the broad ligands of the cyclooctatrienyl (C8H8, Cot) and cyclononatetraenyl (C9H9, Cnt) type. The original
Ordered Porous Inorganic Fluorides as efficient Heterogeneous Catalysts – OPIFCat
The OPIFCat project aims to develop ordered porous inorganic fluorides (FIPO) as active, selective and stable catalysts under catalyzed fluorination conditions of chlorinated organic reagents using anhydrous HF as fluorination agent in the gas phase. More specifically, the objective here is to synth
Orchestration in time and space of southeast Tibetan faults, views from geology and geodesy – Tibetan-Orchestra
Despite decades of controversy, our understanding of the formation of the Tibetan Plateau remains limited. The role of competing mechanisms, such as distributed crustal thickening versus lateral propagation of thrust faulting at crustal or lithospheric scales, is still poorly understood. Conceptual
Oral exposure and gut-targeted toxicity of PFOA and its precursor 8:2 FTOH under chronic stress: when high-resolution chemical imaging bridges food toxicology – FLUO-GUT
Le tractus digestif est la première barrière physique et biologique contre le PFOA après exposition orale, et en même temps sa première cible. Toutefois, ses effets sur la paroi intestinale restent, à ce jour, largement méconnus. Par ailleurs, dans nos sociétés occidentales, l’Homme contemporain est
Optimizing Paralympic performance: from detection to medal-winning
L’objectif est de comprendre les enjeux de la très haute performance paralympique et de proposer des outils au service des athlètes afin d’optimiser leur performance jusqu’aux Jeux de Paris 2024. La Fondation EDF participe au projet grâce à un mécénat de compétence. Trois axes composent le projet :
