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Effect of Titanium dioxide dietary particles on host-gut microbiota interactions: role of aryl hydrocarbon receptor and impact on the development of metabolic disorders and colon cancer. – TitADiet
Particles of TiO2 are used as colorant (additive E171) in several processed food. The aim of TitADiet is to explore the consequences of chronic oral exposure to E171 in the occurrence and/or the aggravation of metabolic disorders and intestinal tumor lesions. A link with intestinal dysbiosis and its consequences on the intestine, immunity and metabolism will be evaluated.
In situ delivery of Interleukin-7 to adjuvant mucosal vaccines – VacMucIL7
We demonstrated that Interleukine-7 (IL-7) is produced in infected mucosae and is able to trigger local expression of chemokines when administered either locally or systemically, leading to massive immune cell homing into targeted mucosae. We hypothesize that locally delivered IL-7 may act as an efficient adjuvant to trigger mucosal immune responses to vaccines.
Light water, heavy water, and sodium chloride aqueous solutions under extreme conditions to shed light on water anomalies and structural properties – H2D2OX
Water is the most anomalous liquid and some of its properties have yet to be measured, especially under extreme temperature and pressure conditions.
Approach of Solar Integration in the Built
Cette formation internationale a démarré à l’automne 2021 avec ses deux parcours : Energy for Solar Buildings
Computation of Resonant Inelastic X-ray Scattering in the condensed phase across the whole periodic table – CompRIXS
This project aims to devise and apply innovative theoretical approaches to simulate Resonant Inelastic X-ray Scattering (RIXS) spectra, whereby we accurately take into account relativistic effects (especially spin-orbit coupling) while at the same time treating electron correlation, relaxation, and environment effects.
Unraveling intra-pulse dynamics and fast energy transfer in silica glass - a pathway for smart processing using ultrafast lasers – INTRALAS
A pathway for smart processing using ultrafast lasers
Live-tracking rhizobial switch from rhizosphere to plant-confined colonization modes – Live-Switch
Legumes establish a beneficial root nodule-forming nitrogen-fixing symbiosis with rhizobia for improved growth. The early stages of this interaction involve key molecular exchanges and the reprogramming of plant cells for bacterial entry. However, little is known about how rhizobia cope with the drastic shift to a confined host environment at this stage. Live-Switch addresses this question by studying the reprogramming of rhizobia and the dialogue with the plant partner at the single cell level.
Lunar tidal Deformation from earth-based and orbital Laser Ranging – LDLR
This project aims at an improved and consistent determination of the tidal deformations of the Moon by a synthesis of the large amount of observation <br /> obtained from Earth-based Lunar Laser Ranging (LLR) and laser altimetry (LA) from lunar orbit and modelings using different inner structure modelings and rheologies. <br />With a better understanding of the Moon deformations, one will have a better view on its inner structure.
Co-construction of adaptation scenarios for managing coastal risks in the context of climate change in coastal communities in France and Quebec – ARICO
A partnership approach to strengthen adaptation to coastal risks in a context of climate change.
Innovative Common Laboratory for Space Spectroscopy – INCLASS
powerful telescope ever launched into space (in 2021). France is strongly engaged in the JWST, particularly
