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Medical Diagnostic by Artificial Intelligence applied to LIBS Elemental Microscopy – dIAg-EM
The overall goal of the DIAg-EM project is to use laser-induced breakdown spectroscopy (LIBS) elemental-microscopy with artificial intelligence processing to identify, localize and quantify pathogen elements present in selected human lung biopsies. We are proposing to develop a deep learning method able to perform, in real time, a non-supervised elemental identification, and to generate quantitative results over large areas of complex human specimens.
Naphthalene C-H Bond Functionalization: New Methodologies and Total Synthesis Application – NaFMeTS
Naphthalene is a key structural core in chemistry as shown by its presence in many bio-active compounds as well as in organic materials. However, reported synthesis are often steppy. The goal of this project is to develop new C-H activation reactions to introduce regioselectively different functionnal groups on naphthalene derivatives and to apply theses methods to natural products synthesis.
Investigating the plasticity and the differentiation potential of epithelial transition zone cells during normal and perturbed homeostasis – StemTZones
At numerous locations of the body, transition zone lies between two types of epithelia are frequently associated with neoplasia involving both type of tissues. These junctions between our organs allow us to have a continuous lining of tissues it is thus essential to understand how they participate in the inter-organ relationship and how crucial they are to preserve organ homeostasis and function.
Combination of Motor Imagery and Muscle Stimulation (MIMS) to promote neuromuscular plasticity during limb immobilization – MIMS
L'immobilisation complète ou partielle du corps est utilisée pour modéliser de manière aiguë la désuétude musculaire. Une blessure aiguë conduit souvent à une période d'immobilisation du membre blessé, ce qui entraîne des altérations drastiques des facteurs neuronaux et musculaires. Le présent projet propose de développer une méthode permettant de prévenir le déclin important de la fonction motrice suite à l'immobilisation du membre, tant au niveau musculaire que nerveux.
WAter in TEM – WATEM
Study of the interaction Water vapor / aerosols at the sub-micrometer scale: follow in real time the water uptake and the dissolution of nanometric particles and their evolution as a function of relative humidity in an Environmental Transmission Electron Microscope (ETEM)
Orchestration in time and space of southeast Tibetan faults, views from geology and geodesy – Tibetan-Orchestra
The eastern edge of the Tibetan Plateau is a key location to study the interplay between strike-slip motions and thickening through time and understand the regional orchestration between lateral propagation and crustal thickening of the plateau .
Enseignement Technologie de LIcence Ouverts
son lancement officiel a eu lieu le 29 janvier 2021, lors d’une réunion avec les membres du consortium [...] dissémination des résultats hors Consortium, en octobre 2021 et juillet 2022. Le recrutement d’une [...] au projet et intégré au site S.mart le 6 avril 2021. Ce site va perdurer au-delà de la fin du projet
Façonner les talents en formation et en recherche à l'Université de Strasbourg
Depuis janvier 2021, l’Université de Strasbourg (Unistra) en partenariat avec le CNRS et l’Inserm dans
Water-based organic semiconductors colloidal dispersions for photovoltaics – WATER-PV
The fabrication of organic photovoltaic (OPV) devices implies the use of halogeno and/or aromatic solvent to process the active layer. In order to make this technology cleaner, it is necessary to move to eco-friendly solvent and water is the best one. This project aims at developing rationally-designed water-based organic semiconductors colloidal dispersions inks.
Synthesis of Fluorinated Ni(IV) Organometallics. – Ni4Rf
Organofluorine compounds are ubiquitous in medicinal chemistry and agrochemistry. However, the creation of C-CF3 bonds mediated by metals is very challenging due to the M-CF3 bond strength. An original strategy to enable an easier reductive elimination of aryl-CF3 derivatives from well-defined aryl-M-CF3 platforms resides in the preparation of high oxidation state organometallics, more prone to be reduced by 2 electrons. The Ni4Rf project seeks to explore this strategy using Ni(III) and Ni(IV).