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Understanding and preventing the photocatalytic cycle responsible for the occurrence of light-struck flavor in white wines and Champagnes – DeLight
Exposure to visible light of certain white wines, rosés and champagnes induces the formation of an organoleptic fault known as the light-struck flavor. The latter is characterized by smell of cooked cabbage, or wet wool and rotten eggs, as well as accentuated bitterness in the mouth. This defect can
Original Scalable Quantum Mechanical Strategies to Refine High-Resolution Crystallographic Structures of Macromolecules – QuMacroRef
The main goal of the project is to propose a new set of fast computational tools in order to routinely refine crystal structures and electron densities of macromolecules (particularly proteins) when sub-atomic (d = 1.0 Å) or ultra-high (d = 0.7 Å) resolution X-ray diffraction data are available. Thi
Differences in language learnability across ages – LangAge
The complexity of learning language is daunting, as several levels of representation have to be acquired simultaneously: the sound structure of words and phrases (phonology), the association between the sound pattern of words and their meaning (lexicon), the internal structure of words and their gra
FoldaRotaxanes for the Versatile Synthesis of Improbable Interlocked Molecules – FoldaRotaxanes
The aim of the project was to synthesize new molecular interlocked architectures named foldarotaxanes. These structures consist in a molecular axle that is surrounded by a macrocycle and a foldamer. Once the chemical access validated, we have studied the influence of the macrocycle (its presence and
Exploring geological resources and reservoirs Integrity by geophysical prospecTING of clays properties from nano to field scale – ExCiTING
The central objective of the project is to improve the geophysical imaging of clay formations and to detect the presence of mineralization that generates a complex resistivity response, from the earth surface to the cover of the targeted reservoirs. The complex resistivity presents an interesting se
Quantitative study of a threshold response of ERK signalling – ERKtivation
We address a long-standing problem of cell signalling: how a cell interprets a graded or variable signal to generate a threshold, or switch-like, response. The project focuses on the extracellular-signal-regulated kinase (ERK) pathway, which is evolutionary conserved and culminates in the phosphoryl
Comparative analysis of ventral sensory neuron specification mechanisms in invertebrate chordates: insights into the origin and the evolution of the vertebrate peripheral nervous system. – VentralPNS
In the course of evolution, vertebrates have acquired unique novel structures compared to the other chordates, their close invertebrate relatives (amphioxus and ascidians). In particular, the neural crest and the ectodermal placodes give rise to the peripheral nervous system (PNS). These transient e
Efficient and sustainable glass surfaces for pharmacy – HEALTHYGLASS
HEALTHYGLASS will determine innovative silicon oxide and oxynitrides (SiOxNy) coatings applied on the internal surface of pharmaceutic vials, in order to obtain efficient and sustainable barrier properties. The targeted function of these coatings is to limit the interaction between the stored drug a
Assessments of vulnerability of mature and secondary forests to climatic water stress in Southeast Asia – CWSSEA
The main duties of co-PI JC Domec is to incorporate species hydraulic traits into a predictive model of whole tree water use in response of declining soil water availability, therefore permitting estimates of forest productivity in water limited environments. He also contributed to the presentation
Deciphering the cell heterogeneity and the spatial distribution of pathogens in food matrices in interaction with microbial communities – PathoFood
The PathoFood project aims at deciphering cell heterogeneity and spatial distribution of pathogens in interactions with the dominant food microbial communities by characterising their local physiology in their micro-environment and modelling bacterial behaviour in food systems. However, this limit d
