Search for a funded project
Innovation and Transformation for Prevention Activity of Professional Risks – ITAPAR
Innovation and Transformation for<br />Prevention Activity of Professional Risks
Analysis and Separation of Complex signals: Exploiting the Time-frequency structure – ASCETE
In this project, our goal is to develop new reassignment techniques robust to noise and that applies in circumstances where the signal exhibits complex time-frequency patterns, such as interference. Meanwhile, neural network and deep learning approaches will also be investigated, to extract meaningful information from time-frequency representations.
Looking for proteins regulating Peptidoglycan synthases – LookingForPegase
The characterization of the mode of action of the PBP regulators studied in this project will contribute to a better understanding of the inner-workings of bacterial cell morphogenesis. In applied terms, it will open new avenues towards the rational design of new antibacterial drugs and new strategies to combat bacterial infections, notably antibiotic resistant-strains.
Polycomb Repressive Complex in Paramecium: interaction with small RNA machinery and substrate specificity – POLYCHROME
Polycomb Repressive Complex 2 (PRC2) trimethylates histone H3 on lysine 27 (H3K27me3), catalyzed by the Enhancer-of-zeste lysine methyltransferase subunit. Despite intensive research, the mechanisms that regulate the activity of the Polycomb complex and control its targeting remain largely enigmatic and are the focus of our research program POLYCHROME.
Could the RAGE-dependent effects of inhaled sevoflurane on lung epithelial permeability help identifying a treatable trait in acute respiratory distress syndrome? – RESPIRE
The acute respiratory distress syndrome (ARDS) is a major cause of respiratory failure and death that still lacks specific therapy. Inhaled sevoflurane is as an anesthetic agent that may be relevant to processes that depend on the receptor for advanced glycation end-products (RAGE) pathway and contribute to mortality in ARDS, namely epithelial injury, impaired alveolar fluid clearance, and lung alveolar-capillary permeability (TAURA project, funded by ANR/DGOS PRTS 2013).
Learning causal effects between phenome and exposome from large amounts of heterogeneous data in human complex diseases – GePhEx
Learning causal effects between phenome and exposome from large amounts of heterogeneous data in human complex diseases.
PARAMOUNT: Production of Aerosol paRticle orgAnic Matter in ClOUds: chamber and laboratory studies, mechanisms, modelling and iNTegration – PARAMOUNT
Demonstrate how and quatify how much the cloud processes contributes to the atmospheric organic aerosol burden.
Chirped Pulse And Resonator In one Spectrometer: A novel combined molecular jet chirped pulse/cavity Fourier Transform MicroWave spectrometer for fast scan, high-resolution, and chiral discrimination – PARIS-FTMW
The chirped Pulse And Resonator In one Spectrometer (PARIS) applies an innovative and resource-efficient approach: Using a smart design, most electronic components are used in a dual-purpose spectrometer while almost all vacuum equipment are shared. Therefore, PARIS is built at much lower costs than two individual spectrometers and exceeds the advantages of both techniques individually: Rapid broadband capabilities, intensity reliability, as well as unrivalled resolving power and sensitivity.
ultra-wide Bandgaps for futuRE high power electronic ApPlications – BREAkuP
The aim of this project is to explore and to develop radically new material systems based on AlN ultra-wide bandgaps for future power devices providing higher robustness and superior temperature operation towards the ultimate all-binary AlN/GaN/AlN heterostructure. The AlN material will enable high efficiency operation beyond 1200 V as well as higher power performances in the millimeter-wave range, which is not currently reachable by GaN devices.
