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Low Loading Asymmetric Catalysis with Helical Chiral Oligoureas – HCO_for_LLAC
Urea-Based Foldamers as Hydrogen-Bond Donor Catalysts for Molecular and Macromolecular Reactions
Pseudo-Chiral Resonators for the Optical Detection of Chiral Molecules – ChiROptMol
Photonic resonators have the ability to resonantly interact with light. This resonant interaction allows to increase the coupling between molecules and light and to tune the light properties with resonant scatterers. Achiral nanostructures with optical activity have the great advantage of enhancing opposite circular dichroism depending on the illumination conditions. This unique feature is at the core of the objectives of this work, which is the detection of chiral biological molecules.
A novel mechanically enhanced bioleaching process – BIOMECALIX
Biomecalix, a mechanically assisted bioleaching process
Roles of Agroforestry in sustainable intensification of small farMs and food Security for Societies in West Africa – RAMSES II
Agroforestry, a promising option for the design of agricultural systems that are sustainable and resilient, particularly in West Africa which is highly vulnerable facing global changes.
Oral exposure and gut-targeted toxicity of PFOA and its precursor 8:2 FTOH under chronic stress: when high-resolution chemical imaging bridges food toxicology – FLUO-GUT
Les substances perfluoroalkylées (PFAS) sont utilisés depuis plus de 60 ans dans un grand nombre de produits industriels. Le PFOA, l'un des représentants majeurs des PFAS, se caractérise par une forte persistance dans l'environnement malgré les restrictions d'utilisation, une présence ubiquitaire et une toxicité avérée. Le projet FLUO-GUT vise à une meilleure compréhension de son devenir après ingestion et des perturbations induites sur la sphère digestive et sur l’axe intestin/foie.
Cellular repair and toxicity determinants of the major oxidative DNA lesion thymine glycol – TG-TOX
Thymine glycol (TG) is a major oxidation product of thymine and 5-methylcytosine in DNA generated by ionizing radiation (IR) and, to a lesser extent, by free radicals of endogenous origin. The present project is a collaborative effort aimed at elucidating of the biological relevance of different repair pathways proposed for TG in the context of living cells
Structural and functional studies of import and intermembrane space transfer of mitochondrial membrane proteins – MitoMemProtImp
Mitochondria perform numerous biological functions. they produce all cellular ATP (i.e. energy) and perform key metabolic reactions. 99% of their proteins are produced outside mitochondria and have to be imported. Here, we study key steps of the import of membrane proteins into mitochondria, namely how chaperones and receptors collaborate to achieve efficient targeted import. We combine structural biology and in-vivo techniques to go from the atomic level to the cellular relevance.
Combining Magnetic Spectroscopy and Modern Multireference Methods to Understand the Properties of Bio-Inspired and Enzymatic Multicopper Systems – CUBISM
Combining Magnetic Spectroscopy and Modern Multireference Methods to Understand the Properties of Bio-Inspired and Enzymatic Multicopper Systems
3D monolithically integrated SPAD pixels in advanced CMOS FDSOI technology – SPAD-FDSOI
This project meets the performance needs of photodetectors (response time, sensitivity, etc.) for applications such as 3D vision, for example facial recognition or navigation aid, medical imaging, etc. but also for potential new applications in cryptography or photonics / quantum optics.
Pristine — A survey of the first Galactic stars – Pristine
The most efficient path to understanding the formation of the Milky Way into a disk galaxy during the first few billion years of the universe is to search for, map, and study the dynamics of primordial stars as these stars are the only remaining witnesses of these very early times.