Leveraging Chemoselectivity with Carbene-Derived Earth-Abundant Polynuclear Metal-Hydride – CarbHydride
As exemplified by the Stryker’s reagent, a phosphine-stabilized hexameric polymetallic copper(I) hydride [(Ph3P)CuH]6 (commercialized by Aldrich) routinely used in stoichiometric or catalytic quantities as a mild and selective reducing agent, Metal-Hydrogen (M-H) bonds occupy an important place in organic synthesis. In this project we intend develop new and original quantum-sized earth-abundant polynuclear metal–hydrides stabilized by carbene ligands for applications in chemoselective transformations of organic substrates.
Project coordination
Rodolphe JAZZAR (UCSD-CNRS Joint Research Chemistry Laboratory)
The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.
Partnership
Engle Lab
ICBMS INSTITUT DE CHIMIE ET BIOCHIMIE MOLECULAIRES ET SUPRAMOLECULAIRES
UCSD-CNRS Joint Research Chemistry Laboratory
UCSD l’Université de Californie San Diego
Help of the ANR 405,189 euros
Beginning and duration of the scientific project:
November 2023
- 48 Months
