LabCom_2021 - V2 - Laboratoires communs organismes de recherche publics – PME/ETI - Edition 2021 - Vague 2

New technologies and engineering laboratory for therapeutic ultrasound – TechnoFUS-Lab

Submission summary

Focused Ultrasound Therapies (FUS, or HIFU for High Intensity Focused Ultrasound) emerged in the 2000s as new therapies, completely non-invasive, based on the physical interaction between the high intensity ultrasound wave and the tissue to be treated. FUS therapies make it possible for example to burn tumors locally, to destroy atheroma plaques by shock waves, or to locally deliver drugs to potentiate their therapeutic effect and limit their side effects. These methods have considerable therapeutic potential, due to their non-invasive, non-ionizing nature. Despite this unique potential, these methods depend on many major technological developments. Their effectiveness and safety can only be guaranteed if the stages of preoperative planning, targeting and real-time monitoring are properly handled. Each represents a real technological challenge, and the recent emergence of these therapies has only been made possible by technological advances in imaging, electronics, instrumentation, among other fields. The LabCom TechnoFUS-Lab aims to prepare the future of therapeutic ultrasound devices through the use of new technologies such as robotics, real-time imaging and microelectronics.

TechnoFUS-Lab is a joint laboratory between the company Image Guided Therapy (IGT, Pessac, France) and the ICube laboratory (CNRS / University of Strasbourg). Image Guided Therapy (IGT) is an SME dedicated to the development and commercialization of ultrasound technologies and minimally invasive, image-guided cancer treatment devices (http://www.imageguidedtherapy.com/). Research and development are at the heart of IGT's activities, which is internationally recognized for its therapeutic ultrasound devices designed for experimental research. IGT is also involved in three different clinical projects using focused ultrasound to treat breast tumors, prostate tumors and bone metastases.



Created in 2013, the ICube laboratory (UMR 7357 CNRS-University of Strasbourg) brings together researchers in the fields of engineering and computer science at the university of Strasbourg, with imaging as a unifying theme. The major fields of application are engineering for health, environment and sustainable development. The laboratory has 650 members divided between 17 research teams. The AVR (Automation, Vision and Robotics) team is recognized for its activities in the fields of medical robotics and mechatronics, interventional imaging, computer-assisted medical and surgical gestures, artificial intelligence, and MRI-guided ultrasound therapies, as evidenced by the ongoing clinical trial on a new device for treating bone tumors under MRI guidance. The LabCom TechnoFUS will rely on the expertise of the members of this team, as well as on ongoing research projects in these fields, in order to allow the the integration of advanced technologies into ultrasound devices offered by IGT. TechnoFUS-Lab will also rely on the expertise of the Heterogeneous Systems and Microsystems (SMH) team at ICube in electronics / microelectronics in order to integrate new solutions for more efficient and optimized electronics of ultrasonic signal control.

The integration of these new technologies will make it possible to overcome some of the major limitations of current devices in therapeutic ultrasound, and the LabCom is expected to have a significant contribution to the large-scale dissemination and acceptance of these unique therapies.

Project coordinator

Monsieur jonathan VAPPOU (ICube Laboratoire des sciences de l'Ingénieur, de l'Informatique et de l'Imagerie)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.

Partner

ICube ICube Laboratoire des sciences de l'Ingénieur, de l'Informatique et de l'Imagerie
IMAGE GUIDED THERAPY IMAGE GUIDED THERAPY

Help of the ANR 362,992 euros
Beginning and duration of the scientific project: March 2022 - 54 Months

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