CE37 - Neurosciences intégratives et cognitives

Investing Space: vestibular stimulation to investigate self-motion perception – In-Vest

Submission summary

How the human brain integrates vestibular input for self-motion perception is the question that we propose to tackle with an innovative strategy by (1) efficiently stimulating the vestibule using galvanic vestibular stimulation (GVS) to trigger a vivid illusion of self-motion, (2) identifying the brain structures involved and their causal roles, (3) measuring the effect of gravity in these processes, as well as (4) the aging one and (5) assessing human specificity versus primates. A 6th step consists in developing in contact with startup companies a high resolution GVS stimulator for both basis science and clinics. CerCo provides expertise in vestibular stimulation, human/monkey fMRI and awake surgery to distinguish human specificities. Clle offers its fNIRS skills to assess the effect of gravity and cognitive aging. The third (LNSC) partner brings gravity and vestibular medicine, as well as technology transfer. On top of their critical value for fundamental knowledge, these achievements will benefit in further studies to major projects in spatial orientation, both on Earth and Space, one of Toulouse pole of excellence, as well as promoting the emergence of new clinical, therapeutic and remediation strategies for vestibular patients who are so far only partially taken over, in optimizing mobility-related interventions and training approaches targeting safe and independent mobility throughout the lifespan.

Project coordination

Alexandra Séverac Cauquil (Centre de Recherche Cerveau et Cognition)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.

Partner

CLLE COGNITION, LANGUES, LANGAGE, ERGONOMIE
LNC Laboratoire de neurosciences cognitives
CerCo Centre de Recherche Cerveau et Cognition

Help of the ANR 604,887 euros
Beginning and duration of the scientific project: December 2021 - 48 Months

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