CE19 - Technologies pour la santé

Spectroscopic LCOCT for cancer diagnosis improvement in dermatology – Spec-LCOCT

Submission summary

Line-field Confocal Optical Coherence Tomography (LC-OCT) is an imaging technique invented by A. Dubois (project coordinator) and developed by DAMAE Medical for non-invasive in situ skin cancer diagnosis by providing a comprehensive cellular mapping of skin lesions based on morphological information. The core of this project is the implementation of several spectroscopic modalities in LC-OCT, based on Raman scattering, fluorescence emission and diffuse reflectance to provide additional information on the local biochemistry of the skin tissue. The combination of spectroscopic measurements with high-resolution morphological information should significantly improve the skin cancer diagnosis accuracy. Combining high spatial resolution (1 µm), deep penetration (~ 1 mm), and molecular contrast in a handheld device should revolutionize skin cancer management and reduce lifetime healthcare costs.

Project coordination

Arnaud Dubois (Laboratoire Charles Fabry)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.


DAMAE Medical DAMAE Medical
LCF-IOGS Laboratoire Charles Fabry
CHU St-Etienne Délégation à la Recherche Clinique et à l'Innovation
CRAN Centre de recherche en automatique de Nancy (CRAN)
Lip(Sys)2 Lipides : Systèmes analytiques et biologiques

Help of the ANR 520,165 euros
Beginning and duration of the scientific project: May 2022 - 36 Months

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