Wireless Endogenous parameter Bio-transduction – WEB

Chronic diseases are responsible for deaths and quality of life impairment. Diabetes, for example, is affecting the daily life of patients that have to constantly follow up their glucose level to stave off dysglycemia episodes. On this ground, Continuous Glucose Monitoring systems (CGM) have recently greatly enhance the patient life. However, (1) CGM sensor accuracy is dropping over time due to the foreign body reaction, and (2) CGM systems are still too heavy due mainly to the battery. The WEB project proposes a leap forward in technology generation with a dedicated implantable electrode-antenna (EA) that integrates glucose biosensor, power source, and wireless data transmission. The EA will also be capable of characterizing the surrounding tissue fibrosis, enabling continuous system self-calibration. Based on an already active collaboration between biologists, electronic engineers and electrochemists, the results of this 4-year project will be validated in-vivo by rodent implantation