SusAn - SusAn

Understanding trade-offs between health and efficiency to improve competitiveness and sustainability of animal production by breeding and management – SusTradeOff

Submission summary

It is hypothesised that intense selection for traits such as liveweight gain and egg/milk yield in production animals has resulted in resources being allocated within the animal to production, at the expense of other physiological processes such as immune function. The SusTradeOff project aims to develop cutting edge technologies to study these trade-offs in two production systems (sheep and poultry): SusTradeOff aims to understand how different dietary protein sources are allocated by animals of different genetic backgrounds between production and immune function and how this allocation is affected by stage of production, disease or vaccination. To achieve these aims, biological materials and proteomics technologies will first be developed to study these trade-offs at the individual animal level, which will facilitate the identification of protein sources and/or targeted protein supplementation to enhance or maintain immune function in the face of high production demands. Population studies in experimental and commercial lines will investigate trade-offs between resilience, immunocompetence and production, providing additional genotypes and phenotypes to select in balanced breeding programmes. Data integration and modelling will provide prediction models for trade-offs and decision making tools that will then be validated at the production level with breeding industry partners under commercial conditions using industry standard operational scenarios. By developing integrated animal health and production management strategies to improve competitiveness and sustainability of animal production, especially by delivering more efficient use of proteins, the SusTradeOff project maps to the 3 Research Areas of the call “SusAn”.

Project coordination

Marie-Hélène Pinard-van der Laan (Institut national de la recherche agronomique)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.


Moredun Research Institute
INRA Institut national de la recherche agronomique centre de Toulouse
Hendrix Genetics
Okologisk landsforening
AU Aarhus University
University of Edinburgh
INRA Institut national de la recherche agronomique

Help of the ANR 202,624 euros
Beginning and duration of the scientific project: March 2017 - 36 Months

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