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Call for proposals for Franco-Californian collaboration on stem cells’ basic research
The ANR is joining the CIRM RFA (Request for Applications, termed Call for Proposals in France) 11-03, BASIC BIOLOGY AWARDS IV (BBA IV) to fund collaborative research projects between Californian researchers and French researchers. The objective of this call for proposals is to fund
Interference MAnaGement for Environmental-friendly NETworks – IMAGE-NET
The main focus of this project is the development of novel interference management techniques in multiuser communication settings under realistic assumptions on the amount of channel knowledge at the nodes, and in the presence of complexity constraints for feasible real time implementation of the pr
Chemical and biological optimization and synthesis of novel heterocyclic 4-amino quinoline-gamma-lactam structures as antimalarials. From «hit» to a potential «lead». – QUINOLAC
A new series of compounds that can be useful as chemotherapeutic agents to treat malaria have demonstrated very potent in vitro activity against P. falciparum strains of variable sensitivity. The originality and novelty of the structures have been demosntrated and their syntheses generate some dive
Microglial Implication in Modulation of Inflammation in leech CNS – MIMIC
Microglial cells are rapidly recruited to a lesion site in the Central Nervous System (CNS) either in mammals or in leech. The program that we develop in the leech aims (i) to characterize the chemotactic factors which are responsible of the microglia migration (ii) to investigate the time-course of
Rac1 E3 ubiquitin-ligase in bacterial invasion and inflammation – RacLig-HPI
The aim of our studies is to determine the implication of the Rac1/HACE1 signaling axis in cell homeostasis and implication upon dysregulation in major human diseases, comprising cancer, inflammatory disorders and infection. Hace1 is a negative regulator of the GTP-bound active form of Rac1. We have
SOil Functional diversity as an Indicator of sustainable management of Agroecosystems – SOFIA
SOFIA project addresses the impact of agricultural practices on the taxonomic and functional diversity of the soil living communities , and the effects on the functions performed by these soils ( greenhouse gas emissions, carbon storage, nutrient availability , biodiversity). The treatments used mod
Management of crop resistance to diseases in agricultural landscapes as a response to new constraints on pesticide use – Gester
The central objective of Gester is to produce scenarios for variety deployment at the scale of agricultural landscapes. As it is currently used, the genetic resistance of the cultivated varieties is poorly durable because of the fast adaptation of pathogen populations. We have shown for instance tha
Structure, Dynamics and Spectroscopy of Ionic Clusters. The synergy between IR-PD experiments and DFT-MD simulations. – SPIONCLUS
The proposed research is an effort to understand the role of non-covalent interactions in formation of secondary structures in biological systems, and the selective sequestration of ions. The focus will be on understanding how intermediate configurations, of higher energy, ultimately reach the groun
How to predict moisture disorders? Which technical solutions to renovate the existing building? – HUMIBATex
Objectives of the project : • Development of a solutions guide about rehabilitation and a description of a validation methodology for adequate solutions of rehabilitation for the non-classified solutions. • Development of a tool to aid in decisions articulating different existing models (indoor cl
TOwards Understanding the sPIn Evolution of Stars – TOUPIES
While the major physical processes impacting on the rotational evolution of solar-type stars are probably identified (magnetized winds, star-disk interaction, internal transport of angular momentum), none is fully understood yet, and few are properly included in stellar evolutionary models. The goal
