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Distribution and consequences of heritable viruses in host-parasitoid communities – viromics
Most insects are hosts to bacterial symbiont. These symbiont may deeply affect the phenotype of the insects in various ways. Nowadays, we begin to have a satisfactorily view of their diversity, their phenotypic effects (ranging from parasitism to mutualism), and circulation in insect communities. In
Development of a monitoring device of the osseointegration of implants in the osteo-articular system – WaveImplant
The aim of this work program is to be ready for the clinical development of the technology using a prototype in line with the market expectations. The program is going on as expected and no particular difficulty is met. Two persons have been hired and two master students work on the subject. An impo
Research of emergent pathogens in Africa – MALEMAF
The techniques of diagnosis in bacteriology in the time of care are quickly changing with the installation of fast molecular detection on targeted micro-organisms. It is possible that in poor and emergent countries, the strategies of culture of the 20th century, which are specialized and heavy, woul
Mechanosensation and mechanostabilization during embryonic morphogenesis – SenStable
The main goal of this proposal is to achieve an integrated understanding of a morphogenetic event involving different tissues during embryonic development. Developmental biologists have reached an in-depth knowledge of the molecular machines controlling most basic cellular processes, and an excellen
Epigenetic reprogramming by the pathogenic bacterium Listeria monocytogenes – EPILIS
It is a priority to characterize, during infection, the molecules that are important for regulating specific genes and to identify which factors alter and are the cause of observed pathologies. Bacterial pathogens can interfere with host nuclear proteins and modify the expression of genes important
AMPc microdomains and structural signaling platforms for the development of retinal projections – MicrocAMP
Cyclic adenosine monophosphate (cAMP) is an intracellular messenger that participates to the organization of retinal axons in their targets of the brain. It regulates a large range of other cellular processes as well, and how specifity for each these signaling pathway is achieved is unknown. Spatial
BrainInSight : a brain-computer interface to decode attention and perception in real time – BrainInSight
At the junction between neuroscience, computer science, and robotics, brain-computer interfaces (BCIs) and neural prosthetics have emerged as a tremendous opportunity to build on core scientific knowledge to alleviate the life of patients with motor disabilities (Lebedev and Nicolelis, 2006; Nicolel
Hunter-gatherers facing environmental changes: the Magdalenian of the Atlantic coast during the Late Glacial (18,000-14,000 cal. BP) – MAGDATIS
Being nomadic and living only from hunting and gathering, Paleolithic people are often perceived - by scholars and by the general public alike - as highly depending on the variations of their natural environment. And indeed, one of the main issues in Paleolithic archeology is to understand the relat
Evo-devo of the diversification and loss of dentition in Birds – PIAFS
Today none of the 11,000 species of birds has teeth, and none of the fossil birds known since the beginning of the Cenozoic (66 million years ago: K-Pg extinction crisis) either. However, most species of birds had teeth earlier, at the time of dinosaurs, the Mesozoic, as well as almost all vertebrat
Differentiation of the Early Silicate Earth: Isotopic Constraints from the Hadean Rock Record – DESIR
There is little question that the first 800 million years of Earth evolution, a period known as the Hadean Eon, was the most geodynamically active in our planet’s history. During this time, the Earth experienced a collision with a Mars-sized embryo (Canup 2004), which likely created a global magma
