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Causation, Probability – CAUSAPROBA
Causation, in particular in its connection to probability, has emerged as one of the most active fields in philosophy of science and its neighboring fields. Still, the current state of research is incomplete; central issues are starting being tackled only in the recent years or are even not really i
Causes and consequences of protein aggregation in cellular degeneration – PAGDEG
In this project, we propose interdisciplinary approaches to improve our understanding of cellular degeneration in relation to aging and, in parallel, to antibiotic treatment of Escherichia coli. This bacterium is not only the best-known organism but also the simplest aging model available. We thus
Caveolae-mediated mechanotransduction: Role in intracellular signaling and cell cholesterol homeostasis – MECHANOCAV
Through a unique combination of biophysics and cell biology, we have recently shown that caveolae, these characteristic small invaginations (60 nm) of the plasma membrane of the cells, are mechanosensors that immediately respond to mechanical stress by flattening. This flattening leads to the releas
Cavitation and Atomization in Nozzles : Numerical and Experimental study – CANNEx
Cavitation is a key phenomenon which must be understood to increase today’s car engine efficiency. Cavitation is a transient phenomenon occurring in region of high velocity gradient and/or low local pressure in nozzle flows. Depending on the type of cavitation, atomization can be enhanced or attenua
Cavitation and Confinement – CAVCONF
Cavitation, i.e. the formation of a vapor bubble in a stretched liquid, is of fundamental interest and plays a central role in many technologies and natural science. For decades, the consensus has been that cavitation occurs via the thermally activated formation of a bubble nucleus as described by t
Cavity quantum electrodynamics with Carbon Nanotubes – NC2
Carbon nanotubes (CNTs) have emerged as original light emitters that trigger both fundamental and technological investigations due to intriguing properties : a large choice of bandgaps covering the telecom bands, low-cost production, extremely robust excitons leading to room temperature emission wit
Cavity-mediated long-range interactions for multiparticle entanglement and quantum simulation – CLIMAQS
Photon-mediated interactions between atoms coupled to an optical cavity are emerging as a powerful tool for engineering many-body Hamiltonians and entangled states. In our project, theorists and experimentalists will collaborate closely to investigate the dynamics of long-range interacting atomic sp
Cell biology of rare earth elements metabolism in Pseudomonas putida – LanthanomiPs
Rare earths elements (REE) are a set of elements with unique properties, used in a variety of high-tech applications and products, and critical to the ongoing energy transition. The recent discovery of enzymes that specifically use REE as a cofactor in a wide range of environmentally important bacte
Cell wall “clicking” as a selective weapon against Streptococcus pneumoniae – PneumoClick
Creating chemical bonds in a controlled manner in a living cell has a great potential of applications in the fields of biology and medicine but remains a major challenge. In the PneumoClick project, we will exploit click chemistry and specificities of the cell wall biosynthesis pathway in the human
Cell-to-cell communication in plants: the possible involvement of membrane rafts in plasmodesmata function – CONNECT
In plants, the intercellular communication through the membrane lined nano-channels called plasmodesmata (PD) plays pivotal roles in the orchestration of development and defence responses. Plant viruses but also fungus can exploit PD transport machinery to establish infection and the emerging view i
