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CHARacterizing Monocyte-Macrophage and B-cell reprogrammING by therapeutic mesenchymal stromal cells in Systemic Sclerosis to improve treatment response – CHARMING-SSc
Systemic sclerosis (SSc) is a rare life-threatening autoimmune disease characterized by lung and skin fibrosis and lacking validated disease-modifying treatments. The use of mesenchymal stromal cells (MSC) is a novel immune reprogramming strategy that could reduce skin and lung fibrosis in severe SS
CHApiTRE : CHAracterization of piRNA cluster expression throughout development and their capacity to tame a sudden TRansposable Element activity – CHApiTRE
Eukaryotic genomes are mainly composed of repeated sequences including transposable elements (TEs), highly mutagenic mobile DNA sequences which constitute a serious threat for the genome integrity. These TEs reside in the genome of all species and represent almost half of the human genome. A fine co
CHApiTRE : CHAracterization of piRNA cluster expression throughout development and their capacity to tame a sudden TRansposable Element activity – CHApiTRE_Ukraine
Eukaryotic genomes are mainly composed of repeated sequences including transposable elements (TEs), highly mutagenic mobile DNA sequences which constitute a serious threat for the genome integrity. These TEs reside in the genome of all species and represent almost half of the human genome. A fine co
CHECKing Membranes And Twisted bilayer oxides for Exotic polar stabilization and Emergent phenomena in multifunctional nanomaterials – CHECKMATE
CHECKMATE aims to fabricate free-standing oxide membranes (OM) and twisted oxide bilayers (TOB) to explore emergent polarization phenomena. By engineering interfacial interactions between ferroelectric (FE) and antiferroelectric (AFE) materials, the project seeks to stabilize novel polar phases at t
CHIRality and luminescence switched ON: a joint theoretical and experimental endeavor – CHIRON
Phosphorescent transition metal complexes (TMCs) possess appealing properties encompassing outstanding photo- and electro-chemical features, highly tunable emission color and relatively long-lived excited states. To date, the vast majority of TMCs used as dopant in light-emitting devices are either
CIRCULATION OF IRON PRODUCTS IN THE IRON-AGE OF EASTERN FRANCE AND SOUTHERN GERMANY: MULTIDISCIPLINARY AND METHODOLOGICAL APPROACHES TOWARDS THE PROVENANCE OF ANCIENT IRON – CIPIA
The aim of the CIPIA program was to consider ferrous metals as a mean to understand a part of economical trade at the end of the Hallstatt and the beginning of La Tène. For the first iron Age (Hallstatt D : 600-475 av. JC), we studied the trade networks linked to ferrous metals and wanted to verify
CISE-ANR: FET: Small: Hybrid Stochastic Tunnel Junction Circuits for Optimization and Inference – StochNet
We will develop digitally compatible, low-barrier magnetic tunnel junctions (MTJs), hybrid measurement and control circuits, and architectures to use their natural stochasticity in the context of various biologically inspired probabilistic computational models. This work is motivated by research in
CITIZENS’ implication in local public decision-making – CITIZENS
We first explore the impact of decentralization on voter turnout and, more specifically, use quasi-experimental methods to assess how different forms of decentralization and different modes of local governance could bring citizens and elected officials closer together at the local level. We also stu
COALITION: From cells over organisms to populations - Characterization of outcomes of emerging alphavirus infections – COALITION
Alphaviruses cause severe acute and chronic disease in humans, including long-term debilitating arthralgia in the case of the epidemiologically most relevant alphavirus Chikungunya virus (CHIKV) that has by now spread across four continents, affecting millions of individuals. In Latin America, CHIKV
CONFLICTS BETWEEN LARGE MARINE PREDATORS AND HUMANS: THE GENESIS AND MANAGEMENT OF PROBLEM INDIVIDUALS – ETHO-PREDATOR
A common misconception is that the emergence of problem animals in populations of large marine predators is the result of external factors that modify the innate, homogeneous behavior of individuals in a given population. Our hypothesis tests the opposite paradigm, which would suggest that, without
