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Branching resource allocation processes for the analysis and inference of phenotypic growth variability – ARBOREAL
Gaining an understanding of the cellular processes underlying bacterial growth is crucial for fundamental research in biology as well as for applications in biotechnology, health, and environmental technology. Growth laws have been formulated that relate growth rate to the macromolecular composition
Breaching the protective cancer stroma with radiotherapy-responsive liposomes – REMOTECONTROL
Liposomes have been the most successful type of nanomedicine for cancer patients, playing a leading role in improving the tolerability of chemotherapeutics. However, to advance the success of liposomal drug delivery and cancer treatment, new approaches to physically trigger drug release in cancer ti
Breaking into the secret conversation between cholesterol and genome stability – GenomeSterolity
The nucleus of the cell, defined by the nuclear membrane, encloses the genetic material, whose maintenance is essential to ensure the homeostasis of cells and organisms. A dedicated surveillance and repair network, believed to be mostly composed by proteins, accomplishes this task in the nucleus. Re
Breast milk as a new paradigm for preserving offspring born from gestational diabetes-mother against adult diabetes – GDM-MILK
The worldwide prevalence of Gestational Diabetes Mellitus (GDM) has increased steadily over the last decade, affecting up to 10.8 % of the pregnancies in France, mainly due to the rising proportion of women with pre-pregnancy overweight, sedentary lifestyle and advanced maternal age at birth. GDM fu
Breathing to Brain Feedback for Recovery during Aversive Learning – Breathing4FearRecovery
This project explores the dual role of breathing in both stress maintenance and recovery following aversive experiences. Our recent findings show that during fear conditioning, mice adopt a 4-6Hz breathing rhythm that sustains freezing behavior, with neuronal oscillations in the olfactory bulb (OB)
Breathing unequally: Air pollution, child development and the reproduction of social inequality; evidence from France – BREATHE
Air pollution has emerged as a key environmental and health issue, linked to about 6.5 million annual deaths worldwide. Increasingly, the literature has also documented impacts on all organ systems, including brain development. Of particular concern is its impact on children and disadvantaged popula
Bridging Artificial Intelligence and Neuroscience – BrAIN
Artificial intelligence (AI) with recent progress in statistical machine learning (ML) is currently aiming to revolutionise how experimental science is conducted. In physics, chemistry, biology, neuroscience or medicine, data is now the driver of new theoretical insights and new scientific hypothese
Bridging the gap between simplified biomimetic systems and cell free extracts to understand actin dynamics. – Golden Gate
Cell shape changes are involved in many cellular processes including cell morphogenesis, establishment of cell polarity and cell motility (Pollard and Borisy, 2003). Cells change shape by exerting internal forces based on dynamical assembly of cytoskeletal proteins. In our project, we will focus on
Brillouin silicon laser based on subwavelength optomechanic waveguides – BRIGHT
This project will address a new route to overcome the trade-off between long phonon lifetimes and large photon-phonon overlap in conventional Si optomechanical waveguides. The original idea is to exploit the unique degrees of freedom released by subwavelength nanostructuration to independently tailo
Bringing the brain of Homo erectus and Neandertals back to life – PaleoBRAIN
To do so, we will investigate for the first time the correlation between the shape of the brain and that of the endocast within a sample of modern humans using MRI acquisitions, including some with a specific sequence (ultrashort echo time, UTE) that allows the characterisation of bone tissues. Comp
