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Targeting FADD for the treatment of heart failure – HFADD
Heart Failure (HF) is an epidemic of the 21st century. This chronic disease is a major public health problem due to its high prevalence (26 million patients worldwide), frequent hospitalizations and economic impact of associated direct and indirect costs. With the aging and industrialization of the
human inspired autonomous navigation in crowds – Hianic
The HIANIC cybercar will analyze its environment by detecting people, evaluating crowd flows, recognizing typical scenarios. It will infer the reaction of the passengers in order to navigate in a way that makes them feel comfortable. Several navigation strategies will collaborate to adapt the moveme
Sustainability and Spatiality in Co-Workers' Mobility Practices – COWORKWORLDS
Coworking spaces appeared in San Francisco in 2005 and since then have spread throughout the world. These new intermediate workplaces between the traditional office and the home are a new way of organizing work based on the sharing of workspace and a network of workers stimulating collaboration. In
Second order optical phenomena in gallium phosphide microdisks on silicon – ORPHEUS
Increase of data flows and energy sustainability push further the limits of information technologies. Integration of photonic circuits (PICs) within microprocessors is a promising option to face these challenges, due to their large bandwidth and low energy cost, but also because light is an appealin
Causality in quantum information – CausaQ
In recent years, quantum information has emerges as one of the raising forces of the information era. Encoding information within quantum systems, and manipulating them in a controlled manner, leads to great gains in terms of information processing. Yet the precise origin of these gains remains, to
Deciphering the role of Human OAS gene family in the pathogenesis of arbovirus infection – ARBOAS
Mosquito-borne viral infections are a major public health problem in tropical countries and are spreading to countries in temperate zone due to climatic change. Dengue, Chikungunya and Japanese encephalitis virus are important mosquito-borne human pathogens causing hemorrhagic, febrile, and severe e
Ergodic properties of the geodesic flow on noncompact manifolds with nonpositive curvature – GEODE
The aim of this project is the study of ergodic properties of geodesic flows on noncompact manifolds with nonpositive curvature. This study is growing rapidly these last few years. Our project gathers together young french researchers who are already working on the subject, to create a dynamical and
Dynamics of Graph Topologies – DynGraph
Graphs (i.e. sets of nodes linked two by two) appear in many contexts. Think of friendship networks, the internet infrastructure, the Web, food webs, road networks, etc. Since the end of the nineties, many works have shown that studying the structure of these graphs, i.e. focusing on the nodes and l
Exploration and Visualization of Dynamic Relational Data – EVIDEN
We have identified three aspects linked to dynamical data. The first concerns the evolution of the network topology. The second relates to the evolution of attributes associated to the elements and/or to the relations between elements. These two aspect both relates to unpredictable evolution of the
RAD51-catalyzed homology recognition and DNA strand exchange: monomer order and dynamics in nucleoprotein filaments assembled on single DNA molecules and during filament interaction with a duplex DNA molecule. – RADORDER
Homologous Recombination is a universal life process essential for maintenance of genome integrity, cell survival and protection against tumorigenesis. Accurate genome duplication, chromosome segregation and repair of DNA double-strand breaks depend on the ability of cells to perform DNA strand exch