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Fate of antibiotics and associated resistance genes in agroecosystems: Ecotoxicological risk for functional microbial communities of the receiving river systems – Antibiotox
Pharmaceuticals including antibiotics, have a wide application range in human and veterinary medicines. It is noteworthy that veterinary antibiotics (VAs) used in livestock and poultry production for growth promotion, prophylaxis and treatment of illness are an important source of environmental cont
Reassortment, Emergence and Factor of Virulence of Influenza A Virus – REACTIV
Influenza A viruses are amongst the most challenging viruses for both human and animal health. The diversity of hosts that they can infect and the frequency of inter-species transmission events maintain the threat of the emergence of strains with high efficiency of spread among humans that could res
3D SOund ReproduCtion using sound-Emitting surfaces in cars – SOURCE
In the foreseeable future, the adoption of multifunctional car structure (MCS) will offer the potential to radically upgrade the abilities of vehicles in terms of ecological requirements emerging from the social and legal environment. Integrating car structures with functional systems that monitor s
Evolutionary and functional impact of epigenetic variations in forest trees. – EPITREE
Forest trees are sessile, long-lived organisms with a major role in the ecology of the Earth. They have developed sensitivity to environmental variation and the potential to adapt, through their high level of standing genetic variations and remarkable phenotypic plasticity. However, forest die-off h
Strategic preemptive pathogen surveillance of air and water to anticipate plant disease emergence in scenarios of changing land use – SPREE
Anticipating emerging infectious diseases and mitigating their impacts are the major challenges of Human, Veterinary and Plant Pathology. Surveillance for the detection of plant diseases and the subsequent response to limit their effects mobilize significant human and economic resources in Europe an
Architectured materials designed with higher-order homogenization – ArchiMatHOS
Recently, additive manufacturing and topology optimization allowed a rupture in material sciences called “material by design” where it becomes possible to design and fabricate materials with a given microstructure. Such materials are referred to as architectured materials because their effective pro
FIRE, foreCASTing and Emergency Response platform – FireCaster
The development of operational services dedicated to mitigate natural and anthropogenic risks is one of the objectives of this ANR call. In the frame of a previous project already led by SPE lab, IDEA (2010-2013 Forest-Fires, from combustion Emissions to Atmospheric transport), considered as a highl
Developing a natural peptide as a novel potent non-opioid analgesic – PeptOPain
There is crucial and unmet need for efficient therapies against chronic pain. Mambalgins represent a real opportunity to develop novel analgesics. These natural peptides specifically block Acid-Sensing Ion Channels, a set of ion channels emerging as important targets in pain. The three isopeptides p
Development of inhibitors specific of cell wall synthesis in mycobacteria – MYCWall
Tuberculosis is the second infectious disease leading to mortality after AIDS and one of the top ten causes of death worldwide. The emergence of multidrug-resistant strains had complicated the management of tuberculosis and constitutes a serious threat for the control of the pandemic. Drugs of the ß
Hydroacoustic SPM measurement technology for operational use – MESURE
Among the great challenges of operational flow monitoring, Suspended Particle Mater (SPM) measurements are of primary importance nowadays because they address several fundamental environmental, industrial and society issues related to the monitoring and prediction of extreme climatic events and thei