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L’origine des processus fondamentaux du développement animal: approche évo-dévo sur les modèles émergents Clytia hemisphaerica (cnidaire) et Pleurobrachia pileus (cténaire) – DiploDevo
Our knowledge of the core mechanisms that regulate animal development relies heavily on intensive experimental work in the classical model organisms, e.g. fruifly, nematode and the vertebrates, all of them belonging to the Bilateria clade of 'higher animals'. It is, however, becoming more and more a
Alimentation des eaux équatoriales par la mer des Salomon : impacts climatiques et bio-géochimiques – SOLWARA
The oceanic circulation in the South Pacific redistributes waters from the large subtropical gyre toward the equator through a subtle journey, mostly suggested by model results and meridional gradients of trace elements. These waters are first transported from the central South Pacific, westward, in
Catalyseurs Supportés sur Nanotubes de Carbone pour Polymérisation d'Ethylène – CANAPE
Carbon nanotubes (CNT) have generated a huge activity in most areas of science and engineering due to their unprecedented physical and chemical properties that make them ideal for a wide range of applications as well as for fundamental science. Functionalized carbon nanotubes are emerging as new too
Calculs intensifs, visualisation scientifique et transfert haut débit international pour des données d?échelle peta: application à l?écoulement dans les voies supérieure de l?Homme – PetaFlow
It is no falsehood to state that `current society and science attempt to deal with increasing amounts of data?. Today, peta-scale data are commonly gathered as well as generated thanks to the continuous development of measurement technologies and computational resources in diverse fields of science
INDUCTION DE TOLERANCE SPECIFIQUE DU TRANSGENE APRES THERAPIE GENIQUE – GENETOL
Several vector systems allow efficient gene transfer and transgene expression in vivo. Recombinant adeno-associated vector (rAAV) is one of them and an increasing number of reports demonstrate that rAAV administered in situ in many different target organs can sustain permanent gene expression after
From neural precursors to glial cells – Epinest
Nervous system, which constitutes the most complex tissue in our entire body, allows us to respond and adjust to the environment. Its sophisticated and stereotypic architecture relies on the differentiation of neurons and glia at specific times and positions from neural stem cells, a source and a re
Towards a comprehensive functional and structural analysis of late Salmonella effector proteins – Typheffects
Salmonellosis is one of the most common and widely distributed bacterial foodborne diseases. Since the beginning of the 1990s problems related to Salmonella have increased significantly and new concerns have been identified. Strains of Salmonella which are resistant to a range of antimicrobials, inc
Small RNA pathways during ES cell differentiation and X inactivation – RNAES
The recent discovery of the RNA interference (RNAi) process and its effector molecules ' small RNAs of 21 - 40 nt - has led to a revolution in our comprehension of gene regulation in many organisms (plants, invertebrates and vertebrates) (Fire et al., 1998; Baulcombe, 2004; Lau et al., 2006; Katiyar
Ontogenèse de la mégacaryopoïèse humaine – Megon
This proposal has for goal to understand the ontogenic changes, which occur during human megakaryopoiesis. The background of this project is related to the fact that some oncogenic events leading to megakaryoblastic leukemia only occur on f'tal progenitors and that the thrombocytopenia of the TAR sy
Design of REliable edge neuromorphic system based on SPINtronics for GREEN AI – RESPINGREEN
Shifting AI inference and training processes from current cloud-based infrastructures towards embedded architectures poses severe challenges, notably in terms of energy efficiency, smaller area needs, reconfigurability, high prediction accuracy and output explainability. Conventional neural network
