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BIsmuth BIfunctional CHElates for Medical APplications of alpha-emitters: design, synthesis, and radiolabelling – BIBI-CHEMAP
Large tumor masses may be currently treated with beta emitters vectors such as yttrium. However, such vectors are not suitable at all for the treatment of diseases related to isolated and / or circulating cells. For these conditions, it is indeed necessary to use alpha emitters, exhibiting a higher
BMP9 as a major regulator of vascular tone in Pulmonary Arterial Hypertension: a promising new therapeutic target – B9inPAH
Cardiovascular diseases are a major economic burden on health care systems and represent one of the leading causes of global mortality and morbidity. These recent years have demonstrated the fundamental role played by BMPs (Bone morphogenetic proteins) in cardiac and vascular development, and that d
BMP9/BMP10/ALK1 pathway: a new mechanism for immunomodulation in vascular diseases – BUILD
Blood vessels and lymphatic vessels are the major transit ways for immune cells, granting access to all peripheral tissues and immune storage sites in lymphoid organs. Emerging evidence from single cell RNA sequencing (scRNA-seq) suggests that specific subtypes of endothelial cells play distinct imm
BRAin INfrared STimulation combined with Optical and electrical Recording using Microelectrode arrays based devices – BRAINSTORM
Functional mapping of the connectivity of the brain is an essential procedure for neurosurgeons aiming for maximal resection of a brain tumor, while minimizing damage to the eloquent cortex. Being able to delineate the location of critical cortical areas in individual patients allows the surgeon to
BREaking the COde of MYelination – BRECOMY
The acquisition of the neural crest and one of its derivatives, the myelin sheath, has largely contributed to the evolutionary success of vertebrates. Without myelin, vertebrates as we know them would not exist. Unfortunately, the occurrence during pathological processes, the most common of which i
BRIDging the environment(al) Gap: promising catalyst materials to performant fuel cells Electrodes – BRIDGE
The large-scale deployment of PEMFCs is hampered by the lack of efficient transfer of highly-active ORR nanocatalysts from ‘beaker’ cells (cells made of glass and filled with liquid electrolyte classically used in academic laboratories) to real MEAs. The main objective of the BRIDGE project is to im
Bacillus anthracis in France : phylogenetic relationships at local, regional and national levels and its involvement in forensic and epidemiologic investigation. – FRANthracis
Anthrax is a zoonotic disease of worldwide distribution caused by a dangerous spore-forming bacterium, Bacillus anthracis. In France, sporadic cases in cattle may be recorded each year. B. anthracis is considered as a major threat in terms of bioterrorism. Responding to both civilian and military c
Bacillus subtilis mRNA metabolism and gene expression : a study on the function and structure of the novel and essential ribonucleases Y and J – RNAJAY
Proteins are synthesized from amino acids using messenger RNA (mRNA) molecules as a matrice in a process called «translation«. These mRNAs represent copies of the genes that code for these proteins. However, in contrast to DNA which is very stable, mRNA is a very fragile molecule which generally has
Back to single caRrier for beyond-5G communications AboVE 90GHz – BRAVE
The BRAVE project proposes to investigate innovative technologies allowing for an efficient radio-communication usage of the 90GHz-200GHz spectrum. It will contribute to the emergence of ultra-high throughput and capacity brought by beyond-5G (B5G) wireless communication systems. The wideband Single
Bacterial degradation and environmental impact of carbon nanotubes – DECANO
Carbon nanotubes (CNTs) represent an emerging nanomaterial for a wide range of applications both in materials science and biomedicine. The increasing production of CNTs, their processing and eventual incorporation into new types of composites and/or into biological systems has raised fundamental iss