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Emergence of an unusual cutaneous leishmaniasis and new endemic foci of Leishmania donovani infections in the Himalayan mountains - Biotic and abiotic determinants. – MANDALA
Considered a major global public health issue, infection by the Leishmania parasite is complex, with more than 20 pathogenic species affecting humans and causing several clinical forms. Visceral leishmaniasis (or Kala-azar) is fatal if left untreated. Cutaneous leishmaniasis, on the other hand, lead
The role of sleep disturbances in the emergence of neuropsychiatric symptoms in aging and neurodegenerative diseases – SENPSY
It is estimated that around 139 million individuals will suffer from dementia worldwide by 2050, with Alzheimer’s disease (AD) and dementia with Lewy Bodies (DLB) being the leading causes. No curative nor preventive treatment is yet available, although disease-modifying therapies for AD do offer som
SORption studies in Adiabatic Falling Films of viscous Ammonia-based working fLuids – SORAFFAL
The SORAFFAL project aims to advance the scientific and technical understanding of adiabatic falling film absorbers using NH3-salt mixtures, with the long-term objective of developing more compact, efficient, durable, and cost-effective absorption chillers. As cooling demand increases rapidly and va
Mechanistic Underpinnings of SOcial BIAS – SO-BIAS
In western countries, people report holding fewer racist and sexist attitudes than a decade ago, yet discrimination and inequalities persist. This issue can be examined at two interrelated levels: the systemic roots of racism and sexism, well-documented by sociological research, and the individual-l
Resilient multimodal transport management with shared autonomous electric vehicles under disruptions – RAISE
Natural disasters, technological failures, and human-caused accidents frequently disrupt public transport lines and infrastructure. This may result in shutdowns of public transport services and shift of travel demand to road networks. Without effective emergency response strategies, urban traffic sy
Planet formation in inner disks enters the observational era – CHAIN
The past decades have witnessed a revolution in planetary science, showing the ubiquitousness of planets around other stars and the striking diversity in their properties. Understanding the origin of this diversity and the routes to the emergence of habitable planets is one of the holy grails of ast
Illuminating the mechanism of action of 4-F4t-Neuroprostane using bioorthogonal chemistry – Ima-ClickChe
Omega-3 polyunsaturated fatty acids (?3-PUFAs) and their derivatives have emerged as key compounds in many biological processes, but their mechanism of action is still obscure. Illuminating this mechanism is thus of critical interest, both for academic and drug design purposes. This is particularly
Historical storm tracks facing climate change in coastal socio-ecological systems – HiStoTracks
In the current context of climate change, coastal extreme events are becoming a major environmental issue. However, many uncertainties remain regarding the evolution of extratropical low-pressure systems at the origin of these storms. In view of the recent occurrences of some major events that have
Small-scale modelling of water quality evolution to anticipate potential impacts on biocide treatment discharges in the context of climate change – Biocide-WATCH
The Biocide-WATCH project addresses the impact of global warming (GW) on water quality, focusing on how these modifications will affect the formation of disinfection by-products (DBPs). The climatic changes, combined with human activities, intensify eutrophication, degrade water quality, and enhance
