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AntiMicrobial Agents from LIchen Associated bacteria – AMALIA
Antibiotic resistance (AR) and persistence of pathogenic microorganisms are emerging threats to human health, as the number of antibiotics effective against resistant bacteria is increasingly scarce. Microbe-host symbiotic interactions often depend on bioactive molecules with an antibiotic potential
Integrative Xer recombination complex Stabilization – InXS
Bacteria have evolved a highly conserved chromosomally encoded recombination machinery, Xer, to resolve chromosome dimers. With the exception of a few species, Xer is composed of two tyrosine recombinases, XerC and XerD, which act on a specific chromosome site, dif. Diverse mobile elements harness X
Heterofunctional Porous Catalysts for Hydrogen Evolution Reaction in Alkaline Electrolyzers – HYKALIN
Anion Exchange Membrane Water Electrolysis (AEMWE) is a very promising technology for producing clean H2 at a target cost of 2 $/kg. Like Proton Exchange Membrane Water Electrolysis (PEMWE), this membrane-based technology has the advantages of an “all solid” system (coupling with intermittent energy
Sustainable water reuse practices improving safety in agriculture, food and environment – SAFE
SAFE will promote positive and practical valorization of reclaimed urban wastewater as a valuable alternative source for agricultural purposes. SAFE will provide a multi-beneficial approach with novel, unconventional and environmental decentralized wastewater solution that will be respectful of envi
Platform for multisCale simulation of hot carriers: electrons and phonons for energy harvesting – PlaCho
The project Placho (Platform for multisCale simulation of hot carriers: electrons and phonons for energy harvesting) aims to develop an original multi scale (DFT+Monte Carlo+NEGF) numerical platform from atoms to device specifically dedicated to energy conversion. This versatile tool based on first
Catalytic Manganese-based anti-oxidants: an integrated approach from chemical design to bio-activity in cells – CATMAN
Superoxide dismutases (SOD) are very efficient redox metalloproteins, which protect the cell from oxidative stress. We have considered manganese SOD (MnSOD) as a model for the design of new Mn-based catalytic antioxidants (MnAOs). They will be studied directly in a cellular context, cells being cons
Development of a CVD plasma assisted process for the synthesis of spherical boron doped diamond core-shells and advanced characterizations – COCONUT
Boron Doped Diamond (BDD) emerges as an outstanding material for electrochemistry, electrocatalysis, photocatalysis and medicine. Wide band gap semiconductor with quasi-metallic behavior at high doping level, resilient to harsh chemical conditions, bioinert, this material gathers serious assets. Amo
SARS-CoV-2 endemization in wildlife of African rainforest following the spread of COVID-19 in the Republic of the Congo – SPILLBACK
Since December 2019, when reports of a new respiratory disease began to emerge from Wuhan, China, COVID-19 has spread worldwide, causing, causing 4 million confirmed cases and 250 000 deaths as of May 5, 2020. Recently, the outbreak has started to spread in Africa, raising major concerns for public
Glycan-dependent mechanical activation of the ß2-adrenergic receptor: a new pathophysiological paradigm – MECAD-R
The present project will investigate several breakthroughs emerging from a previous study, in which we deciphered protein-protein interactions and signalling pathways activated by a bacterial pathogen (N. meningitidis, meningococcus, the agent of cerebrospinal meningitis) to colonize brain vasculatu
Inclusive Museum Guide – IMG
The IMG proposal aims to design, prototype and test a portable multisensory Inclusive Museum Guide (IMG) that will a) make museums accessible to all, b) contribute to the promotion and accessibility of cultural heritage, and c) create in any visitor new aesthetic impressions while experiencing multi
