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Water-soluble aza-BODIPY platform for multimodal imaging and trackable therapeutics – WazaBY
Development of a new class of water-soluble fluorophores, optimized for near infrared imaging (NIR).<br />Functionalitzation of the boron center on the aza-BODIPYs, in order to develop new bimodal and theranostic agents.<br />Valorization of the systems by a preclinical study, aiming at the bimodal imaging and theranostic approach of cancers overexpressing PD-L1.
"Développer les protéines végétales et diversifier les sources de protéines" Volet 2 – Protéines de légumineuses- Appel à projets - 2022
La stratégie nationale « Alimentation durable et favorable à la santé » vise notamment à diversifier la production de sources de protéines pour l’alimentation, pour une alimentation à la fois durable et favorable à la santé. Cette stratégie nationale contribue à l’un des objectifs du Plan France 2030 : investir dans une alimentation saine, durable et traçable.
Field patterns and land use dynamic over time – PARCEDES
The PARCEDES project seeks to evaluate the role of societies and environments in the organisation and transmission of agrarian land parcels over the long term, by comparing four French, English and Italian areas, from the Bronze Age to the present day. PARCEDES also plans to promote and disseminate the sources used and the data and results produced, to the general public and to managers of archives, heritage and contemporary territories.
Unraveling the pathophysiology of Bethlem Myopathy using a unique zebrafish model for the disease – FishandCol6
Bethlem myopathy (BM) is a misunderstood and uncurable disorder characterized by abnormal contractures and muscle weakness. The BM results from mutations in one of the genes encoding the 3 major a-chains of collagen VI (ColVI), a component of the myomatrix, but the mechanisms of action have not been elucidated. Our working hypothesis is that muscle dysfunction caused by BM mutation results from alteration in muscle excitation and/or intracellular Ca2+ homeostasis.
