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Mean time ambulatory emboly counting for stroke risk evaluation. – EMBOLTER
Asymptomatic stenosis will generally not treated except in cases where the embolic nature is proved.
Mechanics of Tissues: multi-scale structural approach of Ehlers-Danlos Syndrome – METIS
re during a mechanical assay was not possible, except in some very specific cases, or through “post-mortem”
Mechanism of inhibition of a novel target of beta-lactam antibiotics – CarbaTub
Emergence of resistance to multiple antibiotics requires the indentification and chartacterization of new targets for drug developement. The aim of our project is to characterize a promising target for the tretament of multidrug resistant tuberculosis
Mechanism of interaction of subgroup B2 adenovirus to the desmosomal cadherin DSG2 and applications – Ad-Cadh
In this ANR, we address three major work-packages consisting of (i) the biochemical and biophysical mapping of the domains of interaction between viruses and their receptor, (ii) the resolution of the atomic structure of the complex they form by cryo-EM and X-ray crystallography and (iii) the study of their bio-distribution in mice after modification or not of the natural tropism.
Mechanisms and consequences of robust PD1 expression by neonatal regulatory T cells in the diabetes-prone NOD mouse – TregNOD
susceptibility locus Idd5.1 contributes to an exceptionally high frequency of PD1-expressing cells among
Mechanisms defining functional heterogeneity of anatomically distinct myogenic populations – MUSE
Not all muscles in the body are the same, even though they share the same basic structure: myofibers, the contractile units, and stem cells that ensure their repair. The muscles of the head — those that control eye movements, swallowing, and speech — have a different embryonic origin from trunk muscles, possess unique modes of contraction, and are not affected by muscle diseases with the same severity as other muscles in the body.
Mechanisms of membrane rupture and repair: viral assembly strategies. – membrane dynamics
understand the role of both lipids and proteins in the unconventional membrane assembly of large DNA viruses
Mechanization and optimization of techniques for the production and harvest forest biomass coming from specific cultures – MECABIOFOR
The development of lignocellulosic energy crops (Short Rotation Coppice or Very Short Rotation Coppice and Semi-Dedicated plantations) is conditioned by technical innovations on plantation, weeding and harvest of these stands. To lower costs, while facilitating the work, is a real challenge.
Membrane processes in ScCO2 medium for economical supercritical processes – MemScCO2
The introduction of regulations or societal demands for less pollution requires green solvents that are less toxic for humans/the environment. Supercritical CO2 is an excellent green solvent, but its use is very energy-intensive.<br />Recycling supercritical CO2 using membrane filtration reduces the energy cost of extracting sunflower oil using supercritical CO2 by more than 90%, making it economically viable.
Menage a trois: a third, feminising sex chromosome. Evolutionary consequences and relevance to mammalian sex determination genetics – SEXREV
Luckily, we have recently identified a mammalian exception to the XY rule. The species of African pygmy mouse [...] of gonadal sex. Mus minutoides is also an exceptional model to understand the evolutionary forces driving [...] neurobiology and molecular genetics), around an exceptional model (for which we are running the only breeding