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Improving models and plant phenotyping pipelines for a smart agriculture under abiotic stress combination and elevated CO2 – MODCARBOSTRESS
Improving phenotyping pipelines and crop models for best prediction of plant performance under climate change
Inborn errors of immunity to HSV-1 underlying childhood herpes simplex encephalitis: an exception or a rule? – IEIHSEER
Childhood herpes simplex virus 1 (HSV-1) encephalitis (HSE) is a devastating viral illness of unclear pathogenesis. HSE is the most frequent form of sporadic viral encephalitis in developed countries
Epigenetics and epigenomics of virus-related hepatocellular carcinomas – EpiVirHep
Epigenetics and hepatocellular carcinoma: impact on pathogenesis and prognosis.
Deciphering multifactorial diseases: insight into oyster mortalities – DECIPHER
<br />Mass and recurrent mortality events of complex etiology have increasingly affected oysters over the past years, To open a way out of this unprecedented crisis and find solutions for a sustainable oyster aquaculture, it is necessary to decipher this complex pathosystem. This is the aim of the DECIPHER project.
International call for proposals "ORA – Open Research Area for the social sciences"
funding rules of each individual agency (with some exceptions detailed below). Proposals may be submitted
Generic call 2015: encouraging international projects
ANR promotes collaborative research in Europe and the world, thereby stimulating the emergence of high-level scientific partnerships between French and foreign teams. To meet this objective, it proposes a funding instrument baptised PRCI, the French acronym for "Collaborative Research Projects - International". This instrument, which can be used under the 2015 generic call for proposals, enables French teams to submit projects in collaboration with a number of other countries.
Role of the TIM and TAM receptors during dengue virus infection – TIMTAMDEN
envelope glycoprotein has yet been identified, except for DC-SIGN in dendritic cells. We recently discovered
Thioamide Activation for the Tuberculosis World – Tea-4-Two
In previous reports, we have shown that small molecule inhibitors of EthR stimulate the transcription of the ethA gene, which improves the bio-activation of ETH and consequently boosts its antibiotic activity, both in vitro and in vivo. However, as expected, these molecules were unable to boost the bio-activation of ETH in strains harboring mutations in ethA. Tea-4-Two is based on the discovery of a new generation of drug molecules that main circumvent the problem of drug resistance to ETH.
Role of Zbtb24 and DNA methylation in late B-cell differention and humoral memory – METHYL-MEMORY
Life-long protection by the humoral immune system is supported by long-lived plasma cells, which constitutively secrete antibodies, and memory B cells, which remain quiescent in the absence of the cognate antigen. As both cell types are affected in patients suffering from the ICF syndrome, the elucidation of the link between the genetic basis of this disease and the immunodeficiency should bring new light on the physiology of these cells and help find new treatments for this disease.
Genesis and maintenance of bacterial secondary chromosomes – MAGISBAC
The MAGISBAC project aims at providing both a global and detailed view of how secondary replicons adapt to their host and become domesticated in bacteria.
