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Mechanism of interaction of subgroup B2 adenovirus to the desmosomal cadherin DSG2 and applications – Ad-Cadh
In this ANR, we address three major work-packages consisting of (i) the biochemical and biophysical mapping of the domains of interaction between viruses and their receptor, (ii) the resolution of the atomic structure of the complex they form by cryo-EM and X-ray crystallography and (iii) the study of their bio-distribution in mice after modification or not of the natural tropism.
Mechanism of inhibition of a novel target of beta-lactam antibiotics – CarbaTub
Emergence of resistance to multiple antibiotics requires the indentification and chartacterization of new targets for drug developement. The aim of our project is to characterize a promising target for the tretament of multidrug resistant tuberculosis
Mechanics of Tissues: multi-scale structural approach of Ehlers-Danlos Syndrome – METIS
re during a mechanical assay was not possible, except in some very specific cases, or through “post-mortem”
Mean time ambulatory emboly counting for stroke risk evaluation. – EMBOLTER
Asymptomatic stenosis will generally not treated except in cases where the embolic nature is proved.
Matériaux fluorés structurés pour sources laser rouge/verte – FLUOLASE
strong demand in visible laser sources. Indeed, excepted for the blue, which can be covered by using the
Matter of glacial origin and its fate in the ocean: a case study at Kerguelen – MARGO
study along the glacier-ocean continuum. The exceptional multidisciplinary knowledge that exists at Kerguelen
Material Culture of Babylonia during the 1st millenium B.C. – MCB
The rich textual data from the Neo-Babylonian Empire in the 6th century BC illustrates processes of manufacturing of artefacts which have not been preserved in their archaeological context. This body of virtual data is exceptional for such an early period. The textual data can be cross-referenced with preserved archaeological data to understand the identity and techniques of those who made them, and how furniture and tools were used.
Mate choice for good genes or compatible genes : an integrative approach with a focus on the major histocompatibility complex – CMatecHoice
Nowdays, biodiversity is disappearing at a speed a thousand times superior to the historical rate, thus mortgaging our future. Mate choice of partner is a true architect of biodiversity.
Mastering the Charge Transfers and Trapping Dynamics in Hybrid Nano-Perovskite/TMDC 2D Photodetectors – MaTra2D
combine two class of model materials displaying exceptional and complementary opto-electronic properties
Mastering Electrons in LOw Dimensional Innovative Carbides (MELODIC) – MELODIC
MXenes are the functional nanomaterials forming the building blocks of an impressive number of potentially useful industrial applications. In all previously published data, there is a clear lack of quantitative information about the basic electron properties.
